Fmoc-Gly-NH-CH2-O-CH2COOH

製品番号: HY-43279 純度: 99.13%: Data Sheet SDS COA 取扱説明書
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Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs.

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Fmoc-Gly-NH-CH2-O-CH2COOH 構造式

CAS 番号 : 1599440-08-0

容量	価格（税別）	在庫状況	数量
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
100 mg	$30	在庫あり	Estimated Time of Arrival: December 31
250 mg	$60	在庫あり	Estimated Time of Arrival: December 31
1 g	$190	在庫あり	Estimated Time of Arrival: December 31
5 g	$935	在庫あり	Estimated Time of Arrival: December 31
10 g	$1868	在庫あり	Estimated Time of Arrival: December 31
25 g	$3736	在庫あり	Estimated Time of Arrival: December 31
50 g		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

ADC Linker アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs^[1].

体外実験

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

384.38

分子式

C₂₀H₂₀N₂O₆

CAS 番号

1599440-08-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)COCNC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 175 mg/mL (455.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6016 mL	13.0080 mL	26.0159 mL
5 mM	0.5203 mL	2.6016 mL	5.2032 mL
10 mM	0.2602 mL	1.3008 mL	2.6016 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.13%

Select Batch:

データシート (269 KB) SDS (393 KB)

COA (247 KB) HNMR (270 KB) RP-HPLC (262 KB) LCMS (98 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Tsuda Toshifumi, et al. Novel cyclic dinucleotide derivative and its antibody-drug conjugate having STING agonist activity. Patent. WO2020050406.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6016 mL	13.0080 mL	26.0159 mL	65.0398 mL
	5 mM	0.5203 mL	2.6016 mL	5.2032 mL	13.0080 mL
	10 mM	0.2602 mL	1.3008 mL	2.6016 mL	6.5040 mL
	15 mM	0.1734 mL	0.8672 mL	1.7344 mL	4.3360 mL
	20 mM	0.1301 mL	0.6504 mL	1.3008 mL	3.2520 mL
	25 mM	0.1041 mL	0.5203 mL	1.0406 mL	2.6016 mL
	30 mM	0.0867 mL	0.4336 mL	0.8672 mL	2.1680 mL
	40 mM	0.0650 mL	0.3252 mL	0.6504 mL	1.6260 mL
	50 mM	0.0520 mL	0.2602 mL	0.5203 mL	1.3008 mL
	60 mM	0.0434 mL	0.2168 mL	0.4336 mL	1.0840 mL
	80 mM	0.0325 mL	0.1626 mL	0.3252 mL	0.8130 mL
	100 mM	0.0260 mL	0.1301 mL	0.2602 mL	0.6504 mL