2. Anti-infection
  3. Fungal Bacterial
  4. Fredericamycin A

Fredericamycin A has anti-Gram-positive bacterial and fungal activity, and shows strong anti-tumor effect in vivo and in vitro.

For research use only. We do not sell to patients.

Fredericamycin A

Fredericamycin A Chemical Structure

CAS No. : 80455-68-1

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Fredericamycin A Related Antibodies

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Description

Fredericamycin A has anti-Gram-positive bacterial and fungal activity, and shows strong anti-tumor effect in vivo and in vitro[1].

Cellular Effect
Cell Line Type Value Description References
A549 EC50
1.8 μM
Compound: 1, FDM A
Cytotoxicity against human A549 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against human A549 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
DU-145 EC50
2.7 μM
Compound: 1, FDM A
Cytotoxicity against human Du145 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against human Du145 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
HCT-15 EC50
2.4 μM
Compound: 1, FDM A
Cytotoxicity against human HCT15 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against human HCT15 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
HT-29 EC50
0.57 μM
Compound: 1, FDM A
Cytotoxicity against human HT29 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against human HT29 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
MCF7 EC50
0.36 μM
Compound: 1, FDM A
Cytotoxicity against human MCF7 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against human MCF7 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
P388D1 EC50
0.05 μM
Compound: 1, FDM A
Cytotoxicity against mouse P388D1 cells by calcein AM/AthD1 fluorometric detection
Cytotoxicity against mouse P388D1 cells by calcein AM/AthD1 fluorometric detection
[PMID: 18232659]
Molecular Weight

539.49

Formula

C30H21NO9
CAS No.
SMILES

O=C1[C@]2(C(C3=C(O)C(C(C=C(C4=O)OC)=O)=C4C(O)=C31)=O)C5=C(O)C(C(NC(/C=C/C=C/C)=C6)=O)=C6C=C5CC2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fredericamycin A Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fredericamycin A80455-68-1FungalBacterialInhibitorinhibitorinhibit

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Fredericamycin A
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HY-N14429
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