2. Apoptosis
  3. Apoptosis
  4. Ganoderic acid S

Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway.

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Ganoderic acid S

Ganoderic acid S Estructura química

No. CAS : 103963-38-8

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Ganoderic acid S Related Antibodies

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Descripciòn

Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway[1].

Cellular Effect
Cell Line Type Value Description References
Vero IC50
> 98 3
Compound: 39
Cytotoxicity against African green monkey Vero cells by green fluorescent protein microplate assay
Cytotoxicity against African green monkey Vero cells by green fluorescent protein microplate assay
[PMID: 26716912]
Vero IC50
>98 3
Compound: 39
Cytotoxicity against African green monkey Vero cells by green fluorescent protein microplate assay
Cytotoxicity against African green monkey Vero cells by green fluorescent protein microplate assay
[PMID: 26716912]
In Vitro

Ganoderic acid S (0, 39.1, 97.7 μM; 12 h) causes cell cycle arrest in the S phase in HeLa cells[1].
Ganoderic acid S dose-dependently causes the collapse of mitochondrial membrane potential. Ganoderic acid S induces a substantial release of cytochrome c from the mitochondria into the cytosol in HeLa cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ganoderic acid S Related Antibodies

Cell Cycle Analysis[1]

Cell Line: HeLa cells
Concentration: 0, 39.1, 97.7 μM
Incubation Time: 12 h
Result: Caused cell cycle arrest in the S phase.
Peso molecular

512.72

Fòrmula

C32H48O5
No. CAS
SMILES

C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)O)C
Structure Classification
Initial Source

Ganoderma lucidum
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Ganoderic acid S Related Classifications

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Keywords:

Ganoderic acid S103963-38-8ApoptosisHeLa cellsGanoderma lucidumMitochondriacervical cancerInhibitorinhibitorinhibit

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Ganoderic acid S
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HY-N11636
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