2. Gene
  3. TRMT112 - tRNA methyltransferase activator subunit 11-2 Gene

TRMT112 - tRNA methyltransferase activator subunit 11-2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TRM112; HSPC152; HSPC170; hTrm112; TRMT11-2

Gene ID: 51504 | Gene type: protein coding

About TRMT112

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,316,460-64,318,596 (from NCBI)

This gene has 6 transcripts (splice variants) and 217 orthologues. Ubiquitous expression in adrenal (RPKM 47.8), ovary (RPKM 46.2) and 25 other tissues.

Summary

Enables protein heterodimerization activity and protein methyltransferase activity. Involved in macromolecule methylation and positive regulation of rRNA processing. Located in nucleoplasm and perinuclear region of cytoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

TRMT112 Products(5)

mRNA Protein Name
NM_001286082.2 NP_001273011.1 multifunctional methyltransferase subunit TRM112-like protein isoform 2
NM_001286084.2 NP_001273013.1 multifunctional methyltransferase subunit TRM112-like protein isoform 3
NM_001372071.1 NP_001359000.1 multifunctional methyltransferase subunit TRM112-like protein isoform 1
NM_001372072.1 NP_001359001.1 multifunctional methyltransferase subunit TRM112-like protein isoform 1
NM_016404.3 NP_057488.1 multifunctional methyltransferase subunit TRM112-like protein isoform 1

TRMT112 Protein Structure

Trm112p

Trm112p: Trm112p-like protein (2 - 112)

  • 0
  • 100
  • 125 a.a.
Protein Preferred Names Protein Names

multifunctional methyltransferase subunit TRM112-like protein

TRM112-like protein

Recombinant TRMT112 Proteins

Cat. No. Product Name Accession Purity
HY-P71644 TRMT112 Protein, Human (His-SUMO) Q9UI30 (1M-125S) ≥95%

Related Diseases

Diseases Alias
Cardiomyopathy, Familial Restrictive, 1

RCM1

Restrictive Cardiomyopathy 1

Rcm

Familial Restrictive Cardiomyopathy 1

Cardiomyopathy, Familial Restrictive 1

Cardiomyopathy, Restrictive, Familial, Type 1

Rcm-1
Williams-Beuren Syndrome

Williams Syndrome

WBS

Wms

Deletion 7q11.23

Monosomy 7q11.23

Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb

Fanconi Schlesinger Syndrome

Beuren Syndrome

Elfin Facies Syndrome

Elfin Facies With Hypercalcemia

Hypercalcemia-Supravalvar Aortic Stenosis

Ws
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15090 TRMT112 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TRMT112 VGNC VGNC:101420
Canis familiaris TRMT112 VGNC VGNC:47855
Felis catus TRMT112 VGNC VGNC:81099
Mus musculus TRMT112 MGD MGI:1914924
Rattus norvegicus TRMT112 RGD RGD:1309710
Others TRMT112 NCBI