THUMPD3 - THUMP domain containing 3 Gene

Homo sapiens

Gene ID: 25917 | Gene type: protein coding

About THUMPD3

This gene has 10 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 18.1), thyroid (RPKM 8.7) and 25 other tissues.

Summary

Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

THUMPD3 Products(2)

mRNA	Protein	Name
NM_001114092.2	NP_001107564.1	tRNA (guanine(6)-N2)-methyltransferase THUMP3
NM_015453.3	NP_056268.2	tRNA (guanine(6)-N2)-methyltransferase THUMP3

THUMPD3 Protein Structure

THUMP

UPF0020

0
100
200
300
400
507 a.a.

Protein Preferred Names

Protein Names

tRNA (guanine(6)-N2)-methyltransferase THUMP3

THUMP domain-containing protein 3

Related Diseases

Diseases

Alias

Cerebellar Angioblastoma

Hemangioblastoma Of Cerebellum

Cerebellar Hemangioblastoma

Chromosome 3pter-P25 Deletion Syndrome

3p- Syndrome	3p Deletion Syndrome
Distal Monosomy 3p	Chromosome 3, Monosomy 3p
3p Partial Monosomy Syndrome	Chromosome 3, Deletion 3p
Chromosome 3p Deletion Syndrome	Del Syndrome
Deletion 3p	Monosomy 3p
Partial Monosomy 3p	Distal 3p Deletion
Monosomy 3pter	Telomeric Monosomy 3p
Chromosome Deletion Syndrome 3pter-P25

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14510	THUMPD3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	THUMPD3	VGNC	VGNC:35855
Rattus norvegicus	THUMPD3	RGD	RGD:1560852
Macaca mulatta	THUMPD3	VGNC	VGNC:79435
Mus musculus	THUMPD3	MGD	MGI:1277973
Felis catus	THUMPD3	VGNC	VGNC:66180

Name
Email *

	Sorry, but the email address you supplied was invalid.