2. Anti-infection
  3. Bacterial
  4. Gloxazone

Gloxazone is an effective anaplasmacide.

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Gloxazone

Gloxazone Chemische Struktur

CAS. Nr. : 2507-91-7

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10 mM * 1 mL in DMSO
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Gloxazone Related Antibodies

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Beschreibung

Gloxazone is an effective anaplasmacide[1].

In Vivo

Gloxazone (5 mg/kg; i.v.) is effective in steers artificially infected with Anaplasma marginale[1].
Gloxazone (0.1-3 mg/kg/day; oral) causes renal papillary necrosis and nephrotoxicity in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molekulargewicht

276.38

Formel

C8H16N6OS2
CAS. Nr.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC(C(/C=N/NC(N)=S)=N\NC(N)=S)OCC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 116.67 mg/mL (422.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6182 mL 18.0910 mL 36.1821 mL
5 mM 0.7236 mL 3.6182 mL 7.2364 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6182 mL 18.0910 mL 36.1821 mL 90.4552 mL
5 mM 0.7236 mL 3.6182 mL 7.2364 mL 18.0910 mL
10 mM 0.3618 mL 1.8091 mL 3.6182 mL 9.0455 mL
15 mM 0.2412 mL 1.2061 mL 2.4121 mL 6.0303 mL
20 mM 0.1809 mL 0.9046 mL 1.8091 mL 4.5228 mL
25 mM 0.1447 mL 0.7236 mL 1.4473 mL 3.6182 mL
30 mM 0.1206 mL 0.6030 mL 1.2061 mL 3.0152 mL
40 mM 0.0905 mL 0.4523 mL 0.9046 mL 2.2614 mL
50 mM 0.0724 mL 0.3618 mL 0.7236 mL 1.8091 mL
60 mM 0.0603 mL 0.3015 mL 0.6030 mL 1.5076 mL
80 mM 0.0452 mL 0.2261 mL 0.4523 mL 1.1307 mL
100 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.9046 mL
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Gloxazone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gloxazone2507-91-7BacterialanaplasmosisAnaplasma marginaleInhibitorinhibitorinhibit

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