HIT-2
HIT-2 is an estrogen receptor alpha (ERα) inhibitor that can bind to the ERα ligand binding domain. HIT-2 forms stable interactions including hydrogen bonds, π-π stacking, and hydrophobic contacts to disrupt ERα-driven signaling. HIT-2 exhibits antineoplastic activity against breast cancer. HIT-2 can be used for the research of breast cancer.
For research use only. We do not sell to patients.
- Formula: C22H20N2O2S
- Molecular Weight:376.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ERα |
HIT-2 is predicted to fallunder Class IV oral toxicity, with an LD50 value of 830 mg/kg, indicating it is harmful if ingested but remains within an acceptable toxicity threshold for early[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 376.47
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Formula C22H20N2O2S
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SMILES
CC(C=C1)=CC=C1C2=NC3=CC=CC=C3S[C@@H](C4=CC(N(O)O)=CC=C4)C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIT-2 Related Classifications
HY-181171 Related Classifications
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