1. Others Anti-infection
  2. Biochemical Assay Reagents Bacterial
  3. HOAT

HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test.

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HOAT

HOAT Estructura química

No. CAS : 39968-33-7

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 g En stock
10 g En stock
25 g En stock
50 g En stock
100 g En stock
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Descripciòn

HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test[1].

In Vitro

HOAT (1.60-5000 μg/plate) shows no mutagenicity in the bacterial reverse mutation (Ames) assay using Salmonella typhimurium strains TA98, TA100, TA1535, TA1537 and Escherichia coli strain WP2 uvrA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ensayo clínico
Peso molecular

136.11

Fòrmula

C5H4N4O

No. CAS
Appearance

Solid

Color

White to yellow

SMILES

ON1C2=NC=CC=C2N=N1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 200 mg/mL (1469.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.3470 mL 36.7350 mL 73.4700 mL
5 mM 1.4694 mL 7.3470 mL 14.6940 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.98%

Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.3470 mL 36.7350 mL 73.4700 mL 183.6750 mL
5 mM 1.4694 mL 7.3470 mL 14.6940 mL 36.7350 mL
10 mM 0.7347 mL 3.6735 mL 7.3470 mL 18.3675 mL
15 mM 0.4898 mL 2.4490 mL 4.8980 mL 12.2450 mL
20 mM 0.3673 mL 1.8367 mL 3.6735 mL 9.1837 mL
25 mM 0.2939 mL 1.4694 mL 2.9388 mL 7.3470 mL
30 mM 0.2449 mL 1.2245 mL 2.4490 mL 6.1225 mL
40 mM 0.1837 mL 0.9184 mL 1.8367 mL 4.5919 mL
50 mM 0.1469 mL 0.7347 mL 1.4694 mL 3.6735 mL
60 mM 0.1224 mL 0.6122 mL 1.2245 mL 3.0612 mL
80 mM 0.0918 mL 0.4592 mL 0.9184 mL 2.2959 mL
100 mM 0.0735 mL 0.3673 mL 0.7347 mL 1.8367 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
HOAT
Cat. No.:
HY-Z0275
Cantidad:
MCE Japan Authorized Agent: