HOAT

Art. -Nr.: HY-Z0275 Reinheit: 99.97%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test.

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HOAT Chemische Struktur

CAS. Nr. : 39968-33-7

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
5 g	Auf Lager	Estimated Time of Arrival: December 31
10 g	Auf Lager	Estimated Time of Arrival: December 31
25 g	Auf Lager	Estimated Time of Arrival: December 31
50 g	Auf Lager	Estimated Time of Arrival: December 31
100 g	Auf Lager	Estimated Time of Arrival: December 31
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This product is a controlled substance and not for sale in your territory.

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
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Beschreibung

In Vitro

HOAT (1.60-5000 μg/plate) shows no mutagenicity in the bacterial reverse mutation (Ames) assay using Salmonella typhimurium strains TA98, TA100, TA1535, TA1537 and Escherichia coli strain WP2 uvrA^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Klinische Studie

Molekulargewicht

136.11

Formel

C₅H₄N₄O

CAS. Nr.

39968-33-7

Appearance

Solid

Color

White to yellow

SMILES

ON1C2=NC=CC=C2N=N1

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 200 mg/mL (1469.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.3470 mL	36.7350 mL	73.4700 mL
5 mM	1.4694 mL	7.3470 mL	14.6940 mL
10 mM	0.7347 mL	3.6735 mL	7.3470 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.98%

Select Batch:

Data Sheet (274 KB) SDS (604 KB)

COA (253 KB) HNMR (121 KB) RP-HPLC (94 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Nicolette J, et al. Peptide bond-forming reagents HOAt and HATU are not mutagenic in the bacterial reverse mutation test. Environ Mol Mutagen. 2016;57(3):236-240. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	7.3470 mL	36.7350 mL	73.4700 mL	183.6750 mL
	5 mM	1.4694 mL	7.3470 mL	14.6940 mL	36.7350 mL
	10 mM	0.7347 mL	3.6735 mL	7.3470 mL	18.3675 mL
	15 mM	0.4898 mL	2.4490 mL	4.8980 mL	12.2450 mL
	20 mM	0.3673 mL	1.8367 mL	3.6735 mL	9.1837 mL
	25 mM	0.2939 mL	1.4694 mL	2.9388 mL	7.3470 mL
	30 mM	0.2449 mL	1.2245 mL	2.4490 mL	6.1225 mL
	40 mM	0.1837 mL	0.9184 mL	1.8367 mL	4.5919 mL
	50 mM	0.1469 mL	0.7347 mL	1.4694 mL	3.6735 mL
	60 mM	0.1224 mL	0.6122 mL	1.2245 mL	3.0612 mL
	80 mM	0.0918 mL	0.4592 mL	0.9184 mL	2.2959 mL
	100 mM	0.0735 mL	0.3673 mL	0.7347 mL	1.8367 mL

HOAT Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HOAT39968-33-7Biochemical Assay ReagentsBacterialTA98Escherichia coli WP2 uvrASalmonella typhimuriumcarboxylic acidsamidesTA1537aminesTA1535TA100peptide bondInhibitorinhibitorinhibit

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HOAT

HOAT Related Antibodies

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität

Reinheit & Dokumentation

Verweise

Kundenbewertung

HOAT Related Antibodies

Molaritätsrechner

Verdünnungsrechner