Lergotrile

Art. -Nr.: HY-107002: Data Sheet Handling Instructions
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Lergotrile is a potent and orally active dopamine agonist and a prolactin secretion inhibitor. Lergotrile inhibits prolactin release from pituitaries by activating an adenohypophyseal dopamine receptor. Lergotrile has the potential for the research of Parkinson's disease.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Lergotrile Chemische Struktur

CAS. Nr. : 36945-03-6

Größe		Verfügbarkeit
MOQ		Minimum order quantity
50 mg		Angebot einholen
100 mg		Angebot einholen
250 mg		Angebot einholen
Other size		Angebot einholen

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

This product is a controlled substance and not for sale in your territory.

Other Forms of Lergotrile:

Lergotrile mesylate Angebot einholen

Spezialitätsempfehlungen

•Related Small Molecules:

•Related Proteins:

Alle Dopamine Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
Sympathetic neuron	ED₅₀	0.27 86 Compound: 2	Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration	[PMID: 6699883]
Sympathetic neuron	ED₅₀	0.27 90 Compound: 2	Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration	[PMID: 6699883]

Molekulargewicht

299.80

Formel

C₁₇H₁₈ClN₃

CAS. Nr.

36945-03-6

SMILES

ClC1=C2C3=C(N1)C=CC=C3[C@]4([H])[C@@](N(C[C@@H](C4)CC#N)C)([H])C2

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Clemens JA, et al. Inhibition of prolactin secretion by lergotrile mesylate: mechanism of action. Acta Endocrinol (Copenh). 1975 Jun;79(2):230-7. [Content Brief]

[2]. Lemberger L, et al. The inhibitory effect of an ergoline derivative (lergotrile, compound 83636) on prolactin secretion in man. J Clin Endocrinol Metab. 1974 Sep;39(3):579-84. [Content Brief]

[3]. Lieberman A, et al. Treatment of Parkinson's disease with lergotrile mesylate. JAMA. 1977 Nov 28;238(22):2380-2. [Content Brief]

Lergotrile Related Classifications

Neurological Disease Endocrinology

Molaritätsrechner
Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lergotrile36945-03-6Dopamine Receptorprolactin secretion inhibitorDopamine AgonistParkinson's diseaseInhibitorinhibitorinhibit

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