[Leu31,Pro34]-Neuropeptide Y (porcine)

Name: [Leu31,Pro34]-Neuropeptide Y (porcine)
Brand: MedChemExpress
SKU: HY-P0208
Rating: 4.5 (1 reviews)

Cat. No.: HY-P0208 Purity: 99.66%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects.

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Custom Peptide Synthesis

[Leu31,Pro34]-Neuropeptide Y (porcine) 화학구조

CAS No. : 125580-28-1

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE [Leu31,Pro34]-Neuropeptide Y (porcine)

•bioRxiv. 2024 May 10.

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•Related Screening Libraries:

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View All Neuropeptide Y Receptor Isoform Specific Products:

View All Isoforms

NPY Y₁ receptor NPY Y₂ receptor NPY Y₄ receptor NPY Y₅ receptor

Biological Activity
순도&문서
References
고객리뷰

제품 설명

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects^[1]^[2].

IC₅₀ & Target^[1]

NPY Y₁ receptor

In Vivo

[Leu31,Pro34]-Neuropeptide Y (porcine) displaces radiolabeled NPY from cells that express Y1 receptors in a series of human neuroblastoma cell lines and on rat PC-12 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

4222.63

화학식

C₁₉₀H₂₈₆N₅₄O₅₆

CAS No.

125580-28-1

Appearance

Solid

Color

White to off-white

Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

Sequence Shortening

YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY-NH2

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : ≥ 100 mg/mL (23.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2368 mL	1.1841 mL	2.3682 mL
5 mM	0.0474 mL	0.2368 mL	0.4736 mL
10 mM	0.0237 mL	0.1184 mL	0.2368 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.66%

Select Batch:

Data Sheet (284 KB) SDS (252 KB)

COA (258 KB) RP-HPLC (266 KB) MS (72 KB) Elemental Analysis Report (119 KB)

Handling Instructions (2659 KB)

References

[1]. Fuhlendorff J, et, al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6. [Content Brief]

[2]. Kokare DM, et, al. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res. 2005 May 10;1043(1-2):107-14. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.2368 mL	1.1841 mL	2.3682 mL	5.9205 mL
	5 mM	0.0474 mL	0.2368 mL	0.4736 mL	1.1841 mL
	10 mM	0.0237 mL	0.1184 mL	0.2368 mL	0.5920 mL
	15 mM	0.0158 mL	0.0789 mL	0.1579 mL	0.3947 mL
	20 mM	0.0118 mL	0.0592 mL	0.1184 mL	0.2960 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.