2. Lipids
  3. Eicosanoids
  4. Thromboxanes

Thromboxanes

Thromboxanes (8):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-113331
    Thromboxane B2 54397-85-2 99.00%
    Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Thromboxane B2 is a biological inactive product and circulating catabolite of thromboxane A2. Thromboxane B2 levels in peripheral venous blood and coronary sinus blood can be used as a diagnostic marker for angina. Thromboxane B2 level in serum is also associated with inhibition of COX-1 activity inhibition in platelets. Thromboxane B2 is a major product of prostaglandin endoperoxide metabolism. Thromboxane B2 produces dose-related decreases in airflow rate, tidal volume and dynamic lung compliance, whilst simultaneously increasing pulmonary airway resistance in dog model. Thromboxane B2 appears to be a naturally occurring bronchoactive metabolite in the bioconversion of arachidonic acid.
    Thromboxane B2
  • HY-113445
    Thromboxane B3 71953-80-5
    Thromboxane B3 is a prostaglandin analog derived from arachidonic acid (AA) in the cyclooxygenase (COX) metabolic pathway. Thromboxane B3 is generated from arachidonic acid (AA) in platelets and vascular endothelial cells through the catalysis of cyclooxygenase (COX) and thromboxane synthase (TXS). Thromboxane B3 has been reported to be formed by human platelets upon ingestion of eicosapentaenoic acid (C20: 5ω3).
    Thromboxane B3
  • HY-113420
    11-Dehydro-thromboxane B2 67910-12-7 99.9%
    11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis.
    11-Dehydro-thromboxane B2
  • HY-137555
    11-dehydro-2,3-dinor Thromboxane B2 79250-60-5 99.0%
    11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.
    11-dehydro-2,3-dinor Thromboxane B2
  • HY-120980
    Thromboxane B1 64626-32-0
    Thromboxane B1 (TXB1) is a stable, inactive endogenous metabolite of Thromboxane A1 (TXA1).
    Thromboxane B1
  • HY-120975
    2,3-Dinor thromboxane b1 196493-76-2
    2,3-Dinor thromboxane b1 is an urinary metabolite of Thromboxane B2 (HY-113331).
    2,3-Dinor thromboxane b1
  • HY-124353
    11-Dehydro thromboxane B3 129228-55-3
    11-Dehydro thromboxane B3 (11-Dehydro-TXB3) is a urinary metabolite of Thromboxane A3 (TXA3).
    11-Dehydro thromboxane B3
  • HY-126923
    2,3-Dinor thromboxane B2 63250-09-9
    2,3-Dinor thromboxane B2 (2,3-Dinor-TXB2), a metabolite of urine, serves as an indicator of the production of thromboxane A2 (TxA2) in the body, and can be used as a tool to study the role of thromboxane in various pathophysiological processes in the human body.
    2,3-Dinor thromboxane B2