Mca-Ala-Pro-Lys(Dnp)-OH

Name: Mca-Ala-Pro-Lys(Dnp)-OH
Brand: MedChemExpress
SKU: HY-P2536
Rating: 5.0 (2 reviews)

Cat. No.: HY-P2536 Pureza: 99.95%: Ficha de datos
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Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.

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Síntesis de péptidos personalizados

Mca-Ala-Pro-Lys(Dnp)-OH Estructura química

No. CAS : 305336-82-7

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

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Revisión del cliente

Based on 2 publication(s) in Google Scholar

2 Publications Citing Use of MCE Mca-Ala-Pro-Lys(Dnp)-OH

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Referencias
Revisión del cliente

Descripciòn

Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung^[1]^[2].

In Vitro

The activity of ACE2 enzyme detected by: the fluorescent peptide substrate Mca-AlaPro-Lys (Dnp)-OH is hydrolyzed by ACE2 and its product is detected by the active fluorescence resonance energy transfer method^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

696.66

Fòrmula

C₃₂H₃₆N₆O₁₂

No. CAS

305336-82-7

Appearance

Solid

Color

Yellow to orange

Sequence Shortening

Mca-AP{K(Dnp)}

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : 50 mg/mL (71.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4354 mL	7.1771 mL	14.3542 mL
5 mM	0.2871 mL	1.4354 mL	2.8708 mL
10 mM	0.1435 mL	0.7177 mL	1.4354 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

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Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.95%

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Ficha de datos (279 KB) SDS (252 KB)

COA (259 KB) RP-HPLC (263 KB) MS (203 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Liu J, Ji H, et al. Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent. Biol Sex Differ. 2010;1(1):6. Published 2010 Nov 5. [Content Brief]

[2]. Liang Y, et al. Urinary angiotensin converting enzyme 2 increases in patients with type 2 diabetic mellitus. Kidney Blood Press Res. 2015;40(2):101-110. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.4354 mL	7.1771 mL	14.3542 mL	35.8855 mL
	5 mM	0.2871 mL	1.4354 mL	2.8708 mL	7.1771 mL
	10 mM	0.1435 mL	0.7177 mL	1.4354 mL	3.5886 mL
	15 mM	0.0957 mL	0.4785 mL	0.9569 mL	2.3924 mL
	20 mM	0.0718 mL	0.3589 mL	0.7177 mL	1.7943 mL
	25 mM	0.0574 mL	0.2871 mL	0.5742 mL	1.4354 mL
	30 mM	0.0478 mL	0.2392 mL	0.4785 mL	1.1962 mL
	40 mM	0.0359 mL	0.1794 mL	0.3589 mL	0.8971 mL
	50 mM	0.0287 mL	0.1435 mL	0.2871 mL	0.7177 mL
	60 mM	0.0239 mL	0.1196 mL	0.2392 mL	0.5981 mL