Aporphine alkaloids from Clematis parviloba and their antifungal activity

Arch Pharm Res. 2009 Jan;32(1):3-5. doi: 10.1007/s12272-009-1111-7.

Jia-Hui Chen ¹, Zhi-Zhi Du, Yue-Mao Shen, Yong-Ping Yang

Affiliations

Affiliation

1 Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Kunming, 650204, Yunnan, China.

PMID: 19183870 DOI: 10.1007/s12272-009-1111-7

Abstract

A new aporphine alkaloid, beta-magnoflorine (1), together with a known aporphine alkaloid, alpha-magnoflorine (2), were isolated from the aerial parts of Clematis parviloba. Their structures were elucidated on the basis of comprehensive spectroscopic techniques. In addition, both compounds showed potent Antifungal activities against Penicillium avellaneum UC-4376.

Products

Cat. No.

Product Name

Description

Target

Research Area
HY-N0535

(+)-Magnoflorine chloride

99.29%, Anti-inflammatory/Anti-tumor/Anti-fungal/Neuroprotective Agent

Fungal; Autophagy; Apoptosis; PINK1/Parkin; NOD-like Receptor (NLR); Caspase; JNK; NF-κB; Sirtuin; AMPK; Reactive Oxygen Species (ROS)

Metabolic Disease; Infection
HY-N0334A

(+)-Magnoflorine iodide

99.74%, Anti-inflammatory/Anti-tumor/Anti-fungal/Neuroprotective Agent

Fungal; Autophagy; Apoptosis; PINK1/Parkin; NOD-like Receptor (NLR); Caspase; JNK; NF-κB; Sirtuin; AMPK; Reactive Oxygen Species (ROS)

Neurological Disease; Metabolic Disease; Inflammation/Immunology; Infection; Cardiovascular Disease; Cancer
HY-N0334

(+)-Magnoflorine

Anti-inflammatory/Anti-tumor/Anti-fungal/Neuroprotective Agent

Fungal; Autophagy; Apoptosis; PINK1/Parkin; NOD-like Receptor (NLR); Caspase; JNK; NF-κB; Sirtuin; AMPK; Reactive Oxygen Species (ROS)

Neurological Disease; Metabolic Disease; Inflammation/Immunology; Infection; Cardiovascular Disease; Cancer

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