1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Monoamine Oxidase B inhibitor 5

Monoamine Oxidase B inhibitor 5 (Compound 16d) is a selective and reversible inhibitor for monoamine oxidase B (hMAO-B) with an IC50 of 67.3 nM and a Ki of 82.5 nM. Monoamine Oxidase B inhibitor 5 exhibits good pharmacokinetic characters and weak toxicity in rats model. Monoamine Oxidase B inhibitor 5 alleviates MPTP-induced (HY-15608) motor impairment in Parkinson’s mouse model. Monoamine Oxidase B inhibitor 5 is blood-brain barrier (BBB) penetrate.

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Monoamine Oxidase B inhibitor 5

Monoamine Oxidase B inhibitor 5 화학구조

CAS No. : 2969160-15-2

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제품 설명

Monoamine Oxidase B inhibitor 5 (Compound 16d) is a selective and reversible inhibitor for monoamine oxidase B (hMAO-B) with an IC50 of 67.3 nM and a Ki of 82.5 nM. Monoamine Oxidase B inhibitor 5 exhibits good pharmacokinetic characters and weak toxicity in rats model. Monoamine Oxidase B inhibitor 5 alleviates MPTP-induced (HY-15608) motor impairment in Parkinson’s mouse model. Monoamine Oxidase B inhibitor 5 is blood-brain barrier (BBB) penetrate[1].

IC50 & Target

hMAO-B

67.3 nM (IC50)

hMAO-A

26014 nM (IC50)

분자량

299.30

화학식

C16H14FN3O2

CAS No.
SMILES

FC1=CC=C(COC2=CC=C(NC(CC(N)=O)=N3)C3=C2)C=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Monoamine Oxidase B inhibitor 5
Cat. No.:
HY-162573
수량:
MCE Japan Authorized Agent: