2. PROTAC
  3. PROTAC Linkers
  4. N-Boc-piperazine

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183).

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N-Boc-piperazine

N-Boc-piperazine Chemical Structure

CAS No. : 57260-71-6

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Other Forms of N-Boc-piperazine:

N-Boc-piperazine Related Antibodies

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Description

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

IC50 & Target

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-Boc-piperazine Related Antibodies
Masse moléculaire

186.25

Formule

C9H18N2O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(OC(C)(C)C)N1CCNCC1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Pureté et documentation

Purity: 99.99%

SDS (393 KB)

COA (246 KB) HNMR (116 KB) GC (177 KB)

Instruction de manipulation (2659 KB)
Références
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N-Boc-piperazine Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Boc-piperazine57260-71-6PROTAC LinkersInhibitorinhibitorinhibit

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Inquiry Information

Nom du produit:
N-Boc-piperazine
Cat. No.:
HY-30105
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SAFETY DATA SHEET (SDS)

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