N3-PEG3-C2-NHS ester

Name: N3-PEG3-C2-NHS ester
Brand: MedChemExpress
SKU: HY-126528
Rating: 4.5 (0 reviews)

Cat. No.: HY-126528 Purity: 99.94%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

N3-PEG3-C2-NHS ester 화학구조

CAS No. : 1245718-89-1

사이즈	재고	수량
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
100 mg	해외재고보유	Estimated Time of Arrival: December 31
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All ADC Linker Isoform Specific Products:

View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
순도&문서
고객리뷰

제품 설명

IC₅₀ & Target

Non-cleavable Linker

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

344.32

화학식

C₁₃H₂₀N₄O₇

CAS No.

1245718-89-1

Appearance

Solid-Liquid Mixture

Color

Colorless to light yellow

SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCN=[N+]=[N-]

선적

Room temperature in continental US; may vary elsewhere.

보관

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (290.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9043 mL	14.5214 mL	29.0428 mL
5 mM	0.5809 mL	2.9043 mL	5.8085 mL
10 mM	0.2904 mL	1.4521 mL	2.9043 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.94%

Select Batch:

Data Sheet (240 KB) SDS (394 KB)

COA (243 KB) HNMR (254 KB) RP-HPLC (213 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9043 mL	14.5214 mL	29.0428 mL	72.6069 mL
	5 mM	0.5809 mL	2.9043 mL	5.8086 mL	14.5214 mL
	10 mM	0.2904 mL	1.4521 mL	2.9043 mL	7.2607 mL
	15 mM	0.1936 mL	0.9681 mL	1.9362 mL	4.8405 mL
	20 mM	0.1452 mL	0.7261 mL	1.4521 mL	3.6303 mL
	25 mM	0.1162 mL	0.5809 mL	1.1617 mL	2.9043 mL
	30 mM	0.0968 mL	0.4840 mL	0.9681 mL	2.4202 mL
	40 mM	0.0726 mL	0.3630 mL	0.7261 mL	1.8152 mL
	50 mM	0.0581 mL	0.2904 mL	0.5809 mL	1.4521 mL
	60 mM	0.0484 mL	0.2420 mL	0.4840 mL	1.2101 mL
	80 mM	0.0363 mL	0.1815 mL	0.3630 mL	0.9076 mL
	100 mM	0.0290 mL	0.1452 mL	0.2904 mL	0.7261 mL