2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. PD 160170

PD 160170 is a compound developed to inhibit low-risk myelodysplastic syndrome-associated anemia with activities that promote red blood cell transfusion independence and increase hemoglobin.

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PD 160170

PD 160170 Estructura química

No. CAS : 181468-88-2

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PD 160170 Related Antibodies

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NPY Y1 receptor NPY Y2 receptor NPY Y4 receptor NPY Y5 receptor

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Descripciòn

PD 160170 is a compound developed to inhibit low-risk myelodysplastic syndrome-associated anemia with activities that promote red blood cell transfusion independence and increase hemoglobin.

Cellular Effect
Cell Line Type Value Description References
SK-N-MC IC50
8.2 1
Compound: 21, PD-160170
Inhibition of forskolin-stimulatedcAMP accumulation in SK-N-MC cells reported as a rightward shift of the NPY dose-response curve at 10 uM concentration
Inhibition of forskolin-stimulatedcAMP accumulation in SK-N-MC cells reported as a rightward shift of the NPY dose-response curve at 10 uM concentration
10.1016/0960-894X(96)00319-8
SK-N-MC IC50
8.2 1
Compound: 21, PD-160170
Inhibition of forskolin-stimulatedcAMP accumulation in SK-N-MC cells reported as a rightward shift of the NPY dose-response curve at 10 uM concentration
Inhibition of forskolin-stimulatedcAMP accumulation in SK-N-MC cells reported as a rightward shift of the NPY dose-response curve at 10 uM concentration
10.1016/0960-894X(96)00319-8
Peso molecular

371.41

Fòrmula

C18H17N3O4S
No. CAS
SMILES

O=S(C1=CC(N)=C(N=CC=C2)C2=C1[N+]([O-])=O)(C3=C(C=CC=C3)C(C)C)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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PD 160170 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD 160170181468-88-2PD160170PD-160170Neuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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Nombre del producto:
PD 160170
Cat. No.:
HY-107724
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MCE Japan Authorized Agent:

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