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Pentetic acid  (Synonyms: Diethylenetriaminepentaacetic acid; DTPA)

Cat. No.: HY-B1335 Purity: 99.80%
Handling Instructions Technical Support

Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide.

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Pentetic acid

Pentetic acid 화학구조

CAS No. : 67-43-6

사이즈 가격 재고 수량
100 mg 해외재고보유
500 mg 해외재고보유
1 g   견적 받기  
5 g   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 3 publication(s) in Google Scholar

Other Forms of Pentetic acid:

Top Publications Citing Use of Products
  • Biological Activity

  • 순도&문서

  • References

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제품 설명

Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide[1][2][3][4].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
264.5 μM
Compound: DTPA
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
[PMID: 18345610]
HepG2 IC50
38.3 μM
Compound: DTPA
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 29233652]
HT-29 IC50
39.1 μM
Compound: DTPA
Cytotoxicity against human HT29 cells after 72 hrs by MTS assay
Cytotoxicity against human HT29 cells after 72 hrs by MTS assay
[PMID: 18345610]
In Vitro

Pentetic acid (0-100 μM, 16 h) inhibits the secretion of elastase in PAO1 cells[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[5]

Cell Line: PAO1
Concentration: 10, 50, 100 μM
Incubation Time: 16 h
Result: Decreased the expression of lasB gene transcription levels.
Clinical Trial
분자량

393.35

화학식

C14H23N3O10

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

DMSO : 5 mg/mL (12.71 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5423 mL 12.7113 mL 25.4227 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • 몰농도 계산기

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5423 mL 12.7113 mL 25.4227 mL 63.5566 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL 12.7113 mL
10 mM 0.2542 mL 1.2711 mL 2.5423 mL 6.3557 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Pentetic acid
Cat. No.:
HY-B1335
수량:
MCE Japan Authorized Agent: