1. Immunology/Inflammation
  2. PGE synthase
  3. (+)-ε-Viniferin

(+)-ε-Viniferin is a stilbenes compound with PGE2 inhibition effect, and is an orally active anti-inflammatory agent. ε-viniferin is also able to reduce fat accumulation, thus can be used for research of inflammation or obesity.

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(+)-ε-Viniferin

(+)-ε-Viniferin Estructura química

No. CAS : 129170-22-5

Tamaño Precio Stock Cantidad
500 μg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
1 mg Obtener un presupuesto 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  
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Descripciòn

(+)-ε-Viniferin is a stilbenes compound with PGE2 inhibition effect, and is an orally active anti-inflammatory agent. ε-viniferin is also able to reduce fat accumulation, thus can be used for research of inflammation or obesity[1][2].

Cellular Effect
Cell Line Type Value Description References
A-375 EC50
>100 μM
Compound: (+/-)-Epsilon-viniferin
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
Antiproliferative activity against human A375 cells after 72 hrs by MTT assay
[PMID: 25826398]
A549 EC50
>100 μM
Compound: (+/-)-Epsilon-viniferin
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
[PMID: 25826398]
HCT-116 EC50
>100 μM
Compound: (+/-)-Epsilon-viniferin
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
[PMID: 25826398]
Platelet IC50
>100 μM
Compound: (+)-epsilon-viniferin
Antiplatelet activity against citreated rabbit platelet assessed as arachidonic acid-induced platelet aggregation
Antiplatelet activity against citreated rabbit platelet assessed as arachidonic acid-induced platelet aggregation
[PMID: 15730246]
Platelet IC50
>100 μM
Compound: (+)-epsilon-viniferin
Antiplatelet activity against citreated rabbit platelet assessed as inhibition of 9,11-dideoxy-11 alpha, 9 alpha epoxy-methanoprostaglandin F2alpha-induced platelet aggregation
Antiplatelet activity against citreated rabbit platelet assessed as inhibition of 9,11-dideoxy-11 alpha, 9 alpha epoxy-methanoprostaglandin F2alpha-induced platelet aggregation
[PMID: 15730246]
SK-MEL-2 EC50
>100 μM
Compound: (+/-)-Epsilon-viniferin
Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay
Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay
[PMID: 25826398]
Peso molecular

454.47

Fòrmula

C28H22O6

No. CAS
SMILES

OC(C=C1)=CC=C1/C=C/C2=C3[C@H](C4=CC(O)=CC(O)=C4)[C@@H](C5=CC=C(C=C5)O)OC3=CC(O)=C2

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación
Referencias
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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
(+)-ε-Viniferin
Cat. No.:
HY-N10755
Cantidad:
MCE Japan Authorized Agent: