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  6. (+)-Coclaurine

(+)-Coclaurine  (Synonyms: (+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine)

Cat. No.: HY-N2550
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(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form ((+)-Coclaurine hydrochloride) usually boasts enhanced water solubility and stability.

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(+)-Coclaurine

(+)-Coclaurine Chemical Structure

CAS No. : 2196-60-3

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Other In-stock Forms of (+)-Coclaurine:

Other Forms of (+)-Coclaurine:

(+)-Coclaurine Related Antibodies

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Description

(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity[1][2].

Cellular Effect
Cell Line Type Value Description References
H9 EC50
0.8 6
Compound: R-coclaurine
Inhibition of HIV replication in H9 cells
Inhibition of HIV replication in H9 cells
[PMID: 18316190]
H9 EC50
2.8 3
Compound: 121
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
[PMID: 20187635]
H9 EC50
2.8 3
Compound: 121
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
[PMID: 20187635]
H9 EC50
2.8 3
Compound: 121
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
[PMID: 20187635]
H9 EC50
0.8 6
Compound: R-coclaurine
Inhibition of HIV replication in H9 cells
Inhibition of HIV replication in H9 cells
[PMID: 18316190]
In Vivo

An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Masse moléculaire

285.34

Formule

C17H19NO3
CAS No.
SMILES

OC(C=C1)=CC=C1C[C@@H]2C3=CC(O)=C(OC)C=C3CCN2
Structure Classification
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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(+)-Coclaurine Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Coclaurine2196-60-3(+)-(R)-Coclaurine(R)-Coclaurine d-CoclaurineOthersBenzyltetrahydroisoquinolinealkaloidpostsynapticInhibitorinhibitorinhibit

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