(+)-Coclaurine hydrochloride
Based on 1 Customer Validation
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity.
For research use only. We do not sell to patients.
- Purity: 99.09%
- CAS No.: 19894-19-0
- Formula: C17H20ClNO3
- Molecular Weight:321.80
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 19894-19-0
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Appearance Solid
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Molecular Weight 321.80
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Formula C17H20ClNO3
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Color White to off-white
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SMILES
COC(C=C(CCN1)C([C@H]1CC2=CC=C(C=C2)O)=C3)=C3O.Cl
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Synonyms
(+)-(R)-Coclaurine hydrochloride; (R)-Coclaurine hydrochloride; d-Coclaurine hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (155.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 5 mg/mL (15.54 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. [1]Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951. [Content Brief]
[2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.1075 mL | 15.5376 mL | 31.0752 mL | 77.6880 mL |
| 5 mM | 0.6215 mL | 3.1075 mL | 6.2150 mL | 15.5376 mL | |
| 10 mM | 0.3108 mL | 1.5538 mL | 3.1075 mL | 7.7688 mL | |
| 15 mM | 0.2072 mL | 1.0358 mL | 2.0717 mL | 5.1792 mL | |
| DMSO | 20 mM | 0.1554 mL | 0.7769 mL | 1.5538 mL | 3.8844 mL |
| 25 mM | 0.1243 mL | 0.6215 mL | 1.2430 mL | 3.1075 mL | |
| 30 mM | 0.1036 mL | 0.5179 mL | 1.0358 mL | 2.5896 mL | |
| 40 mM | 0.0777 mL | 0.3884 mL | 0.7769 mL | 1.9422 mL | |
| 50 mM | 0.0622 mL | 0.3108 mL | 0.6215 mL | 1.5538 mL | |
| 60 mM | 0.0518 mL | 0.2590 mL | 0.5179 mL | 1.2948 mL | |
| 80 mM | 0.0388 mL | 0.1942 mL | 0.3884 mL | 0.9711 mL | |
| 100 mM | 0.0311 mL | 0.1554 mL | 0.3108 mL | 0.7769 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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