2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. PonatiLink-1-24

PonatiLink-1-24 is an Abelson murine leukemia (ABL) enzyme inhibitor.

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PonatiLink-1-24

PonatiLink-1-24 화학구조

CAS No. : 2941512-45-2

사이즈 재고
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PonatiLink-1-24 Related Antibodies

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제품 설명

PonatiLink-1-24 is an Abelson murine leukemia (ABL) enzyme inhibitor[1].

Cellular Effect
Cell Line Type Value Description References
K562 EC50
0.87 nM
Compound: Ponati Link-1-24
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
[PMID: 37849551]
K562 EC50
26.29 nM
Compound: Ponati Link-1-24
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
[PMID: 37849551]
분자량

2120.73

화학식

C101H144ClF5N12O29
CAS No.
SMILES

CC1=C(C#CC2=CN=C3N2N=CC=C3)C=C(C(NC4=CC=C(CN5CCN(C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C6CCN(C7=C(C8=CC=NN8)C=C(C(NC9=CC=C(OC(F)(Cl)F)C=C9)=O)C=N7)CC6)=O)=O)CC5)C(C(F)(F)F)=C4)=O)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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PonatiLink-1-24 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PonatiLink-1-242941512-45-2Bcr-AblInhibitorinhibitorinhibit

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상품명:
PonatiLink-1-24
Cat. No.:
HY-155290
수량:
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