1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Ephrin/Eph Family
  4. Ephrins
  5. Ephrin B2
  6. Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc)

Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc)

Cat. No.: HY-P73019
Handling Instructions

Ephrin-B2 (EFNB2) is a member of the ephrin family. Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Ephrin-B2/EFNB2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc) is 201 a.a., with molecular weight of ~55 kDa.

For research use only. We do not sell to patients.

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Description

Ephrin-B2 (EFNB2) is a member of the ephrin family. Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Ephrin-B2/EFNB2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc) is 201 a.a., with molecular weight of ~55 kDa.

Background

Ephrin-B2, also known as EFNB2, is a protein that plays a crucial role in cellular communication and tissue development. Belonging to the ephrin family, Ephrin-B2 is a transmembrane protein that acts as both a ligand and a receptor, mediating bidirectional signaling events. Its primary function is to interact with Eph receptors on neighboring cells, initiating a cascade of intracellular signals that regulate various cellular processes, including cell adhesion, migration, and tissue patterning. Ephrin-B2 is particularly implicated in angiogenesis, the formation of new blood vessels, where it governs endothelial cell behavior and influences vascular development. Additionally, it has been associated with diverse physiological and pathological processes, such as neuronal guidance, immune response, and cancer progression. Understanding the intricate functions of Ephrin-B2 is crucial for unraveling its therapeutic potential in various medical contexts.

Species

Rat

Source

HEK293

Tag

C-hFc

Accession

B2B9A9 (R29-A229)

Gene ID

306636  [NCBI]

Molecular Construction
N-term
EFNB2 (R29-A229)
Accession # B2B9A9
hFc
C-term
Synonyms
Ephrin-B2; LERK-5; HTK-L; EFNB2; EPLG5
AA Sequence

MAMARSRRDSVWKYCWGLLMVLCRTAISRSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKEQADRCTIKKENTPLLNCARPDQDVKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNNDPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNLLGSEVA

Molecular Weight

Approximately 55 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Ephrin-B2/EFNB2 Protein, Rat (HEK293, Fc)
Cat. No.:
HY-P73019
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