1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EGF Superfamily
  4. Neuregulins
  5. Neuregulin-3 (NRG3)
  6. Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His)

Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His)

Cat. No.: HY-P75944
COA Handling Instructions

Neuregulin-3/NRG3 Protein, a vital neuregulin family member, influences cellular signaling and development, contributing to diverse biological processes. Its unique structural characteristics, lacking conserved residues crucial for feature annotation propagation, hint at distinct regulatory mechanisms or interactions. This peculiarity within the neuregulin family underscores the need for further investigation into NRG3's precise role in cellular signaling and its potential implications in various physiological contexts. Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His) is the recombinant human-derived Neuregulin-3/NRG3 protein, expressed by HEK293, with C-His labeled tag. The total length of Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His) is 61 a.a., with molecular weight of ~8.5 kDa.

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Description

Neuregulin-3/NRG3 Protein, a vital neuregulin family member, influences cellular signaling and development, contributing to diverse biological processes. Its unique structural characteristics, lacking conserved residues crucial for feature annotation propagation, hint at distinct regulatory mechanisms or interactions. This peculiarity within the neuregulin family underscores the need for further investigation into NRG3's precise role in cellular signaling and its potential implications in various physiological contexts. Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His) is the recombinant human-derived Neuregulin-3/NRG3 protein, expressed by HEK293, with C-His labeled tag. The total length of Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His) is 61 a.a., with molecular weight of ~8.5 kDa.

Background

The Neuregulin-3/NRG3 Protein is a member of the neuregulin family, playing a significant role in cellular signaling and development. As part of this family, NRG3 contributes to diverse biological processes, including cell growth, differentiation, and tissue development. Notably, the protein lacks conserved residue(s) crucial for the propagation of feature annotation, suggesting unique structural characteristics or functional properties within the neuregulin family. The absence of these conserved residues may hint at distinct regulatory mechanisms or interactions specific to NRG3, warranting further investigation into its precise role in cellular signaling and its potential implications in various physiological contexts.

Species

Human

Source

HEK293

Tag

C-His

Accession

B9EGV5 (E282-P342)

Gene ID
Molecular Construction
N-term
NRG3 (E282-P342)
Accession # B9EGV5
His
C-term
Synonyms
Pro-NRG3; Neuregulin-3; NRG-3; NRG3
Molecular Weight

Approximately 8.5 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Neuregulin-3/NRG3 Protein, Human (61a.a, HEK293, His)
Cat. No.:
HY-P75944
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