S-Methylglutathione

Name: S-Methylglutathione
Brand: MedChemExpress
SKU: HY-W009177
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製品番号: HY-W009177 純度: 99.40%: Data Sheet SDS COA 取扱説明書
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S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH. S-Methylglutathione has inhibitory effect on glyoxalase 1.

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S-Methylglutathione 構造式

CAS 番号 : 2922-56-7

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 60	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 60	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$55	在庫あり	Estimated Time of Arrival: December 31
10 mg	$80	在庫あり	Estimated Time of Arrival: December 31
25 mg	$150	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

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純度とドキュメンテーション
参考文献
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製品説明

S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH^[1]. S-Methylglutathione has inhibitory effect on glyoxalase 1^[2].

体外実験

S-Methylglutathione (GS-Me) is a stronger nucleophile than GSH, which is rationalized by the more positive inductive effect of the methyl group^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

321.35

分子式

C₁₁H₁₉N₃O₆S

CAS 番号

2922-56-7

Appearance

Solid

Color

White to off-white

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Sealed storage, away from moisture
Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

H₂O : 25 mg/mL (77.80 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1119 mL	15.5594 mL	31.1187 mL
5 mM	0.6224 mL	3.1119 mL	6.2237 mL
10 mM	0.3112 mL	1.5559 mL	3.1119 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.40%

Select Batch:

データシート (270 KB) SDS (396 KB)

COA (244 KB) HNMR (267 KB) RP-HPLC (110 KB) MS (192 KB) Elemental Analysis Report (104 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Foye WO, et al. Synthesis and evaluation of N-alkanoyl-S-benzyl-L-cysteinylglutamic acid esters as glyoxalase I inhibitors and anticancer agents. J Pharm Sci. 1984 Apr;73(4):559-61. [Content Brief]

[2]. Milos I. Djuran,et al. Reactivity of chloro- and aqua(diethylenetriamine)platinum(II) ions with glutathione, S-methylglutathione, and guanosine 5'-monophosphate in relation to the antitumor activity and toxicity of platinum complexes. Inorg. Chem. 1991, 30, 12, 2648–2652

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.1119 mL	15.5594 mL	31.1187 mL	77.7968 mL
	5 mM	0.6224 mL	3.1119 mL	6.2237 mL	15.5594 mL
	10 mM	0.3112 mL	1.5559 mL	3.1119 mL	7.7797 mL
	15 mM	0.2075 mL	1.0373 mL	2.0746 mL	5.1865 mL
	20 mM	0.1556 mL	0.7780 mL	1.5559 mL	3.8898 mL
	25 mM	0.1245 mL	0.6224 mL	1.2447 mL	3.1119 mL
	30 mM	0.1037 mL	0.5186 mL	1.0373 mL	2.5932 mL
	40 mM	0.0778 mL	0.3890 mL	0.7780 mL	1.9449 mL
	50 mM	0.0622 mL	0.3112 mL	0.6224 mL	1.5559 mL
	60 mM	0.0519 mL	0.2593 mL	0.5186 mL	1.2966 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.