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Cd28

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  • HY-P77621
    CD28 Protein, Canine (HEK293, His)

    Cd28 antigen (Tp44); Cd28 molecule; Cd28; MGC138290

    		 Canine HEK293
    CD28 Protein plays a pivotal role in T-cell activation, promoting cell proliferation, cytokine production, and T-cell survival. Upon ligation with TCR/CD3 and CD40L costimulation, CD28 enhances the production of IL4 and IL10 in T-cells, contributing to immune response modulation. Additionally, isoform 3 of CD28 facilitates CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. The protein forms homodimers through disulfide linkages and interacts with various molecules. CD28 Protein, Canine (HEK293, His) is the recombinant canine-derived CD28 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P77622
    CD28 Protein, Canine (HEK293, mFc)

    Cd28 antigen (Tp44); Cd28 molecule; Cd28; MGC138290

    		 Canine HEK293
    CD28 Protein plays a pivotal role in T-cell activation, promoting cell proliferation, cytokine production, and T-cell survival. Upon ligation with TCR/CD3 and CD40L costimulation, CD28 enhances the production of IL4 and IL10 in T-cells, contributing to immune response modulation. Additionally, isoform 3 of CD28 facilitates CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. The protein forms homodimers through disulfide linkages and interacts with various molecules. CD28 Protein, Canine (HEK293, mFc) is the recombinant canine-derived CD28 protein, expressed by HEK293 , with C-mFc labeled tag.
  • HY-P75320
    CTLA-4 Protein, Canine (HEK293, His)

    Cytotoxic T-lymphocyte associated protein 4; CTLA4; Cd152

    		 Canine HEK293
    CTLA-4 protein inhibits T-cell responses as a critical negative regulator, with a stronger affinity for CD80 and CD86 than CD28. This affinity allows CTLA-4 to effectively suppress T-cell activation and regulate immune responses, maintaining a delicate equilibrium in T-cell-mediated immunity. CTLA-4 Protein, Canine (HEK293, His) is the recombinant canine-derived CTLA-4 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75321
    CTLA-4 Protein, Canine (HEK293, Fc)

    Cytotoxic T-lymphocyte associated protein 4; CTLA4; Cd152

    		 Canine HEK293
    CTLA-4 protein inhibits T-cell responses as a critical negative regulator, with a stronger affinity for CD80 and CD86 than CD28. This affinity allows CTLA-4 to effectively suppress T-cell activation and regulate immune responses, maintaining a delicate equilibrium in T-cell-mediated immunity. CTLA-4 Protein, Canine (HEK293, Fc) is the recombinant canine-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag.

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