16 Results for "

18:0 PI

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "18:0 PI" in MCE Product Catalog:

Cat. No.: HY-N16138
CAS No.: 849412-67-5
Synonyms: DSPI (18:0/18:0)
Target:  

Others

Research Areas:  

Metabolic Disease

18:0 PI is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.
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Cat. No.: HY-100355
CAS No.: 2304-81-6
Purity:  99.95%
Synonyms: C18-Ceramide
C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .
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Cat. No.: HY-NP180
Progesterone/BSA is a conjugate of Progesterone (HY-N0437) and bovine serum albumin (BSA). Progesterone/BSA cannot penetrate the plasma membrane of human sperm, but still rapidly elevates intracellular free calcium and induces the acrosome reaction. Progesterone/BSA can also act as a probe to specifically bind to progesterone-binding proteins on the membrane of rat brain synaptosomes .
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Cat. No.: HY-W020658S
Synonyms: DSPI (18:0/18:0)-d6
18:0 PI-d6 (DSPI(18:0/18:0)-d6) is the deuterated form of 18:0 PI. 18:0 PI is a membrane-bound signaling molecule that is associated with almost all aspects of cell physiology, including cell growth, metabolism, proliferation, and survival .
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Cat. No.: HY-175407
Target:  

Drug Derivative

Research Areas:  

Others

18:0-20:4 PI(3,4,5)P3 (sodium) is an analogue of phosphatidylinositol. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC .
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Cat. No.: HY-N16128
CAS No.: 849412-49-3
Synonyms: PI(18:0/0:0)
Target:  

Others

Research Areas:  

Metabolic Disease

18:0 Lyso PI is a lysophosphatidylinositol.
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Cat. No.: HY-157645
CAS No.: 2260669-67-6
Research Areas:  

Others

18:0-20:4 PI(4)P ammonium is a fatty acid.
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Cat. No.: HY-157648
CAS No.: 2315262-42-9
18:0-20:4 PI(3)P ammonium can be obtained by phosphorylation of the inositol ring of phosphatidylinositol and can be used in the preparation of liposomes.
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Cat. No.: HY-157652
CAS No.: 799268-60-3
Synonyms: 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1′-myo-inositol-3′,4′,5′-trisphosphate ammonium
18:0-20:4 PI(3,4,5)P3 (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium)) is a kind of biochemical reagent.
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18:0-20:4 PI(5)P diammonium
0 Images
D-myo-Inositol, 5-(dihydrogen phosphate) 1-[(2R)-2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]oxy]-3-[(1-oxooctadecyl)oxy]propyl hydrogen phosphate], ammonium salt (1:2)
Cat. No.: HY-157640
CAS No.: 2315262-43-0
18:0-20:4 PI(5)P (diammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.
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Cat. No.: HY-164662
CAS No.: 1144075-38-6
Target:  

mTOR PI3K

Research Areas:  

Cancer

mTOR inhibitor-24 (comounp 9d) is a mTOR inhibitor, with IC50s of 0.34 nM (mTOR) and 324 nM (PI3K-α) respectively. mTOR inhibitor-24 inhibtis LNCaP cell proliferation (IC50: 180 nM) .
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Cat. No.: HY-157643
CAS No.: 799268-59-0
Target:  

Liposome

Research Areas:  

Others

18:0-20:4 PI (4,5) P2 triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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Cat. No.: HY-157649
CAS No.: 799268-58-9
Target:  

Liposome

Research Areas:  

Metabolic Disease

18:0-20:4 PI (3,5) P2 triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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Cat. No.: HY-178984
CAS No.: 3095278-75-1
PI3Kα-IN-28 (Compound 23) is an efficient dual targeted PI3K/BRD4 inhibitor. PI3Kα-IN-28 can inhibit the proliferation of various cells, such as KYSE180 and KYSE450 cells. PI3Kα-IN-28 can concentration dependently inhibit migration and colony formation, induce G0/G1 phase arrest, significantly inhibit DNA synthesis, and significantly increase the proportion of senescent cells. PI3Kα-IN-28 can inhibit the expression of p-AKT and c-Myc and activate the AMPK-p27 pathway. PI3Kα-IN-28 can be used for research on cancers such as esophageal cancer .
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Cat. No.: HY-L180
645 compounds

Mitochondrial autophagy refers to the selective encapsulation and degradation of damaged mitochondria by cells through the autophagy mechanism, thereby maintaining mitochondrial and cellular homeostasis. The concept of mitochondrial autophagy has received extensive attention since it was proposed. Current studies have shown that the mechanisms of mitochondrial autophagy can generally be divided into two categories: Ubiquitin-dependent pathways and Ub-independent pathways. In addition, mitochondrial autophagy is a research hotspot related to the pathogenesis of neurodegenerative diseases, cardiovascular diseases, cancer, metabolic diseases and other clinical diseases. Therefore, high-throughput screening based on mitochondrial autophagy can effectively screen out compounds that are closely related to the occurrence of diseases and analyze their mechanisms.

MCE can provide a library of 645 mitophagy compounds, which can be used for drug development and mechanism research in cancer, immunity, infection and other hot research fields.

Cat. No.: HY-P71306
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINB9; Testicular Tissue Protein Li 180; Prev. PI9; SerPIn B9; CAP3; CAP-3; Cytoplasmic Antiproteinase 3; PI-9; Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 9; SerPIn Peptidase Inhibitor, Clade B, Member 9; SerPIn Peptidase In
Species:  
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