1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. C18-Ceramide

C18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis.

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C18-Ceramide Chemical Structure

C18-Ceramide Chemical Structure

CAS No. : 2304-81-6

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5 mg USD 80 In-stock
10 mg USD 135 In-stock
25 mg USD 300 In-stock
50 mg USD 510 In-stock
100 mg USD 867 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

C18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis[1].

Molecular Weight

565.95

Formula

C36H71NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 10 mg/mL (17.67 mM; Need ultrasonic)

DMF : 1 mg/mL (1.77 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7669 mL 8.8347 mL 17.6694 mL
5 mM 0.3534 mL 1.7669 mL 3.5339 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF / Ethanol 1 mM 1.7669 mL 8.8347 mL 17.6694 mL 44.1735 mL
Ethanol 5 mM 0.3534 mL 1.7669 mL 3.5339 mL 8.8347 mL
10 mM 0.1767 mL 0.8835 mL 1.7669 mL 4.4174 mL
15 mM 0.1178 mL 0.5890 mL 1.1780 mL 2.9449 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
C18-Ceramide
Cat. No.:
HY-100355
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