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Results for "

Amphiphilic peptide

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

3

Biochemical Assay Reagents

17

Peptides

2

Oligonucleotides

Cat. No. Product Name Target Research Area
  • HY-P5307

    INF7-A5K-TAT

    Biochemical Assay Reagents Others
    Peptide A5K (INF7-A5K-TAT) is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .
  • HY-W007599

    Drug Derivative Cancer
    (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer for non-viral gene delivery in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid can be used in the preparation of organic substances that enhance the luminescence intensity of alkaline phosphatase substrates .
  • HY-P4121

    Potassium Channel Inflammation/Immunology Cancer
    L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
  • HY-P5284

    Peptides Others
    RALA peptide is a cationic amphiphilic delivery agent targeting cell membranes, which forms nanoparticles through electrostatic interactions with anionic drugs. RALA peptide has pH-responsive binding properties, which can enhance the α-helical conformation in an acidic environment and destroy the endosomal membrane, promote the release of drugs into the cytoplasm, and exert efficient intracellular delivery activity. RALA peptide can be used in cancer research (enhancing the activity of bisphosphonates against prostate cancer and breast cancer cells) and bone tissue engineering (promoting osteoblast collagen deposition and extracellular matrix mineralization) .
  • HY-P2530

    Peptides Others
    KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors .
  • HY-P10649A

    Peptides Cancer
    CPP12 TFA is a small, amphipathic, cyclic cell-penetrating peptide (CPP). CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and then efficiently escapes from endosomes. CPP12 TFA can be used for the intracellular delivery of drugs and chemical probes .
  • HY-P10514

    Small Interfering RNA (siRNA) Others
    Transportan 10 is a derivative of Transportan (HY-P1732) and is an amphiphilic cell penetrating peptide (CPP). Transportan 10 helps molecules penetrate cell membrane barriers by directly interacting with the lipid bilayer. Transportan 10 can be used in gene therapy or siRNA delivery vector research .
  • HY-P5727
    HR1

    Bacterial Infection
    HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can induce cytoplasmic membrane permeation in bacteria and mast cells .
  • HY-P1631

    Bacterial Infection
    Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges .
  • HY-P5307A

    INF7-A5K-TAT acetate

    Biochemical Assay Reagents Others
    Peptide A5K (INF7-A5K-TAT) acetate is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K acetate can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K acetate enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .
  • HY-P11220

    Bacterial Interleukin Related Infection
    Hs02 is a cationic amphiphilic antibacterial peptide derived from human proteins, and it is the membrane-active module of the core chimeric peptide Chim2. Hs02 exhibits broad-spectrum and potent antibacterial activity against various human pathogenic bacteria with the MIC for Staphylococcus aureus and Escherichia coli of as low as 2 μM, and the MBC is 2-4 μM. Hs02 primarily kills bacteria by disrupting the integrity of the bacterial cell membrane, and it has a relatively low selectivity for eukaryotic cell membranes. Hs02 induces the release of IL-12 but does not induce the release of IL-6, indicating its potential for pro-inflammatory or immune activation. Hs02 can be used in antibacterial and immunomodulatory research .
  • HY-P5067

    Peptides Others
    EAK16-II is an amphipathic peptide that inhibits the self-sorting of EAKIIH6 in a concentration-dependent manner .
  • HY-P10443

    Peptides Others
    ppTG20 is an amphiphilic cell penetrating peptide (KALA) that can be used for gene transfection. ppTG20 can bind to DNA, destabilize membranes, and mediate DNA transfection .
  • HY-P10455

    Bacterial Infection
    Cys-Pexiganan TFA is an amphiphilic antimicrobial peptide. Cys-Pexiganan TFA exhibits antibacterial activities against Staphylococcus aureus and Pseudomonas aeruginosa, with MIC of 16 μg/mL and 64.0 μg/mL. Cys-Pexiganan TFA interacts with anionic phospholipids and DNA of microbial cell membranes, disintegrates the cells and leads to cell death .
  • HY-122297

    Peptides Others
    H-​Arg-​Phe-​OH is an amphipathic peptide. H-​Arg-​Phe-​OH has the ability to induce native-like protein aggregation. H-​Arg-​Phe-​OH can induce aggregation of the neutral model protein yeast alcohol dehydrogenase (ADH) .
  • HY-P10520

    Peptides Others
    RWmix is ??a synthetic cell-penetrating peptide. The secondary amphiphilic nature of RWmix promotes cellular uptake, mainly due to the alternating arrangement of arginine and tryptophan. The presence of tryptophan enhances the anchoring of the peptide to the cell membrane, thereby improving its ability to penetrate the cell membrane. RWmix can be used for gene therapy and siRNA delivery research .
  • HY-P11218

    Peptides Cancer
    Lipo-PtIV-R8K is a nuclear targeting peptide containing R8K. Lipo-PtIV-R8K is a lipid PtIV prodrug amphiphilic molecule that can self assemble to form nanoparticles. Lipo-PtIV-R8K can be used in the research of cancer such as breast cancer .

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