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Results for "

Angiotensin+1-7

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

6

Peptides

3

Natural
Products

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12403
    Talfirastide
    Maximum Cited Publications
    17 Publications Verification

    TXA127; Angiotensin (1-7); Ang-(1-7)

    		 Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
    Talfirastide
  • HY-15778
    AVE 0991
    10+ Cited Publications

    		 Angiotensin Receptor Cardiovascular Disease Endocrinology
    AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM .
    AVE 0991
  • HY-P1656
    (D-Pro7)-Angiotensin I/II (1-7)
    1 Publications Verification

    		 Angiotensin Receptor Mas-related G-protein-coupled Receptor (MRGPR) Cardiovascular Disease
    (D-Pro7)-Angiotensin I/II (1-7) is a potent Mas receptor inhibitor with a Ki of 0.001 μM for rat receptors. (D-Pro7)-Angiotensin I/II (1-7) competitively blocks the binding of Angiotensin-(1-7) to the Mas receptor and attenuates the vasodilatory effect of rat aortas under physiological and hypertensive conditions. (D-Pro7)-Angiotensin I/II (1-7) can be used for studies on the function of the renin-angiotensin system and the pathological mechanisms of hypertension .
    (D-Pro7)-Angiotensin I/II (1-7)
  • HY-12403A
    Talfirastide acetate
    Maximum Cited Publications
    17 Publications Verification

    TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate

    		 Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .
    Talfirastide acetate
  • HY-12403R
    Talfirastide (Standard)

    TXA127 (Standard); Angiotensin (1-7) (Standard); Ang-(1-7) (Standard)

    		 Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite Reference Standards Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Talfirastide (Standard) is the analytical standard of Talfirastide. This product is intended for research and analytical applications. Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
    Talfirastide (Standard)
  • HY-P0216A
    A-779 TFA

    		Angiotensin Receptor Cardiovascular Disease
    A-779 TFA is a selective angiotensin-(1-7) (Ang-(1-7)) antagonist. A-779 TFA blocks Arachidonic acid release, bradykinin potentiation effects and hypotensive action. A-779 TFA exerts diuretic effects in non-pregnant rats, antidiuretic effects in late-pregnant rats, and also inhibits feed intake and water consumption in late-pregnant rats. A-779 TFA attenuates the regulatory effects of prostacyclin, nitric oxide and thromboxane A2 associated with angiotensin-(1-7). A-779 TFA can be used in studies related to hypertension .
    A-779 TFA
  • HY-167153
    PNA5

    		Interleukin Related Reactive Oxygen Species (ROS) Cardiovascular Disease Neurological Disease Inflammation/Immunology
    PNA5 is a novel, blood-brain barrier permeable glycosylated angiotensin-(1-7) peptide and MasR agonist. PNA5 inhibits IL-7, increases IL-10. PNA5 inhibits ROS generation, decreases Iba-1 expression. PNA5 exhibits sustained cognitive protective effects. PNA5 rescues blunted cerebral functional hyperemia. PNA5 can be used in the research of inflammation-related brain diseases .
    PNA5

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