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Results for "

ETO

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151411
    RUNX1/ETO tetramerization-IN-1

    		RUNX Cancer
    RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor of RUNX1/ETO tetramerization, exhibits anti-leukemic effect. RUNX1/ETO tetramerization-IN-1 specifically targets to NHR2 of RUNX1/ETO (EC50=0.25 μM), restores gene expression down-regulated by RUNX1/ETO. RUNX1/ETO tetramerization-IN-1 inhibits the proliferation of RUNX1/ETO-depending SKNO-1 cells, and reduces the RUNX1/ETO-related tumor growth in a mouse model .
    RUNX1/ETO tetramerization-IN-1
  • HY-174367
    RUNX1/ETO-IN-1

    		RUNX Apoptosis Cancer
    RUNX1/ETO-IN-1 is a RUNX1-ETO oncogenic fusion protein inhibitor that specifically targets the NHR2 oligomerization domain. RUNX1/ETO-IN-1 directly interacts with the NHR2 (KD,app = 39 μM). RUNX1/ETO-IN-1 exhibits anti-leukemic activity by inducing apoptosis and promoting differentiation in RUNX1/ETO-translocated AML cells. RUNX1/ETO-IN-1 remains essentially uncharged at physiological pH, demonstrating superior membrane permeability.
    RUNX1/ETO-IN-1
  • HY-RS12350
    RUNX1T1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RUNX1T1 Human Pre-designed siRNA Set A contains three designed siRNAs for RUNX1T1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RUNX1T1 Human Pre-designed siRNA Set A
    RUNX1T1 Human Pre-designed siRNA Set A
  • HY-B1336R
    Furazolidone (Standard)

    		Reference Standards Bacterial Apoptosis Antibiotic Parasite Infection Cancer
    Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM.
    Furazolidone (Standard)

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