RUNX1T1 (ETO) Antibody (YA7856)
(Synonyms: AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2)RUNX1T1 (ETO) Antibody (YA7856) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RUNX1T1 (ETO).
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
ICC/IF
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
RUNX1T1 (ETO) Antibody (YA7856) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RUNX1T1 (ETO).
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Calculated Molecular Weight Predicted band size: 63 kDa
Full length human recombinant protein of human RUNX1T1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
RUNX1T1 transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12. Acts as a negative regulator of adipogenesis. The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal[1][2][3][4][5][6].
-
Subcellular Localization
Nucleus
-
Expression
Tissue_Specificity: Most abundantly expressed in brain. Lower levels in lung, heart, testis and ovary -
Isoforms & Post-Translational Modification
Q06455 has 6 isomers: Q06455-1: 67566 Da (predicted); Q06455-2: 64396 Da (predicted); Q06455-3: 68746 Da (predicted); Q06455-4: 63212 Da (predicted); Q06455-5: 48146 Da (predicted); Q06455-6: 44975 Da (predicted).
-
Subunit
Homooligomer
-
SwissProt ID
-
Synonyms
AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Documentation
Powered by Bioz
