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Results for "

Gentiana

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (1) COX (1) TNF Receptor (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (3) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5070

Depressine

Depressin
Others Others

Depressine is a natural product found in Gentiana depressa .

Depressine Depressin	Others	Others
Depressine is a natural product found in Gentiana depressa .

HY-N9096

Gentiside B	Others	Neurological Disease
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .

HY-N9139

Gelidoside

Others Others

Gelidoside is a acylsecoiridoid glucoside isolated from the aerial parts of Gentiana gelida .

Gelidoside	Others	Others
Gelidoside is a acylsecoiridoid glucoside isolated from the aerial parts of Gentiana gelida .

HY-N9000

Loganic acid 6′-O-β-D-glucoside	TNF Receptor	Inflammation/Immunology
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells .

HY-N3862

Erythrodiol 3-O-palmitate	Others	Cancer
Erythrodiol 3-O-palmitate is a natural product isolated from Dicranostigma leptopodum (Maxim) Fedde, Gentiana rhodantha Franch or Swertia kouitchensis. Erythrodiol 3-O-palmitate has antitumor activity, and inhibits the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL .

HY-N9733

2-Methoxyanofinic acid

Others Others

2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla .
HY-N8305

Gentianose

Others Others

Gentianose is a predominant carbohydrate reserve found in the storage roots of perennial Gentiana lutea .
HY-N5080

Isoscoparin

Others Inflammation/Immunology

Isoscoparin is a flavonoid that could be isolated from EtOAc extract of Gentiana algida Pall. Isoscoparin possesses antioxidant activity .

2-Methoxyanofinic acid	Others	Others
2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla .

Gentianose	Others	Others
Gentianose is a predominant carbohydrate reserve found in the storage roots of perennial Gentiana lutea .

Isoscoparin	Others	Inflammation/Immunology
Isoscoparin is a flavonoid that could be isolated from EtOAc extract of Gentiana algida Pall. Isoscoparin possesses antioxidant activity .

HY-N0481

Roburic acid	COX	Inflammation/Immunology
Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC₅₀s of 5 and 9 μM for COX-1 and COX-2, respectively .

HY-N2447

Amarogentin 2 Publications Verification	AMPK Apoptosis	Metabolic Disease Cancer
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

Depressine Depressin	Monophenols other families Classification of Application Fields Source classification Other Diseases Phenols Plants Disease Research Fields	Others
Depressine is a natural product found in Gentiana depressa .

Gentiside B	Structural Classification Gentiana rigescens Franch. ex Hemsl. Source classification Gentianaceae Phenols Polyphenols Plants	Others
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .

Gelidoside	Structural Classification Gentiana gelida M.Bieb. Polysaccharides Source classification Gentianaceae Plants Saccharides	Others
Gelidoside is a acylsecoiridoid glucoside isolated from the aerial parts of Gentiana gelida .

Loganic acid 6′-O-β-D-glucoside	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Gentianaceae Plants Inflammation/Immunology Disease Research Fields Gentiana rhodantha Franch. ex Hemsl.	TNF Receptor
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells .

Erythrodiol 3-O-palmitate	Triterpenes Structural Classification Terpenoids Source classification Dicranostigma leptopodum (Maxim.) Fedde Plants Papaveraceae	Others
Erythrodiol 3-O-palmitate is a natural product isolated from Dicranostigma leptopodum (Maxim) Fedde, Gentiana rhodantha Franch or Swertia kouitchensis. Erythrodiol 3-O-palmitate has antitumor activity, and inhibits the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL .

2-Methoxyanofinic acid	Structural Classification Gentiana macrophylla Pall. Ketones, Aldehydes, Acids Source classification Gentianaceae Plants	Others
2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla .

Gentianose	Polysaccharides other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Saccharides	Others
Gentianose is a predominant carbohydrate reserve found in the storage roots of perennial Gentiana lutea .

Isoscoparin	Flavonoids Classification of Application Fields Source classification Gentianaceae Phenols Polyphenols Plants Gentiana algida Pall. Disease Research Fields Inflammation/Immunology Isoflavones	Others
Isoscoparin is a flavonoid that could be isolated from EtOAc extract of Gentiana algida Pall. Isoscoparin possesses antioxidant activity .

Roburic acid	Triterpenes Gentiana macrophylla Pall. Classification of Application Fields Terpenoids Source classification Gentianaceae Plants Disease Research Fields Inflammation/Immunology	COX
Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC₅₀s of 5 and 9 μM for COX-1 and COX-2, respectively .

Amarogentin 2 Publications Verification	Structural Classification Gentiana scabra Bunge Iridoids Classification of Application Fields Terpenoids Source classification Gentianaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	AMPK Apoptosis
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

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Gentiana

Inhibitors & Agonists

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