1. Epigenetics
    PI3K/Akt/mTOR
    Apoptosis
  2. AMPK
    Apoptosis
  3. Amarogentin

Amarogentin 

Cat. No.: HY-N2447 Purity: 98.96%
Handling Instructions

Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK.

For research use only. We do not sell to patients.

Amarogentin Chemical Structure

Amarogentin Chemical Structure

CAS No. : 21018-84-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 116 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 300 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1000 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK[1][2][3].

Molecular Weight

586.54

Formula

C₂₉H₃₀O₁₃

CAS No.

21018-84-8

SMILES

C=C[[email protected]]([[email protected]@]1([H])C(C(OCC1)=O)=CO2)[[email protected]@H]2O[[email protected]@](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]3O)([H])[[email protected]@H]3OC(C4=C(C5=CC(O)=CC=C5)C=C(O)C=C4O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Amarogentin
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