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Results for "

Iduronate sulfatase

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Inhibitory Antibodies

1

Natural
Products

1

Recombinant Proteins

2

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P991047
    Anti-CD71/TfR1 Antibody

    JR-141 antibody (uncoupled from Iduronate 2-sulfatase)

    		 Transferrin Receptor Neurological Disease Cancer
    Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71/TfR1) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Anti-CD71/TfR1 Antibody
  • HY-P99797
    Pabinafusp alfa

    JR-141

    		 Transferrin Receptor Neurological Disease
    Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
    Pabinafusp alfa
  • HY-P990724
    Tividenofusp alfa

    DNL-310

    		 Steroid Sulfatase Metabolic Disease
    Tividenofusp alfa (DNL‑310) is a modified iduronate‑2‑sulfatase fusion protein capable of crossing the blood-brain barrier. Tividenofusp alfa can be used in research on mucopolysaccharidosis type II .
    Tividenofusp alfa
  • HY-W654272
    4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium

    4-MU-α-idoa 2-sulfate sodium

    		 Fluorescent Dye Metabolic Disease
    4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .
    4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium
  • HY-108826
    Iduronate sulfatase

    Iduronate sulfate sulfatase

    		 Endogenous Metabolite Metabolic Disease
    Iduronate sulfatase (Iduronate sulfate sulfatase) is an exo-sulfatase that hydrolyzes the C2-sulfate ester bond from nonreducing terminal α-L-iduronic acid residues in HS .
    Iduronate sulfatase
  • HY-P992048
    AGT-182

    HIRMab; SHP-631; TAK-531

    		 Insulin Receptor Metabolic Disease
    AGT-182 (HIRMab; SHP-631; TAK-531) is a brain-penetrating anti-human insulin receptor antibody and iduronate-2-sulfatase conjugation. AGT-182 can be used for the research of mucopolysaccharidosis type II (MPS II, Hunter syndrome) .
    AGT-182

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