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IDS (Iduronate 2 sulfatase) Antibody (YA8288)

(Synonyms: MPS2; SIDS)

IDS (Iduronate 2 sulfatase) Antibody (YA8288) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IDS (Iduronate 2 sulfatase).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • IDS (Iduronate 2 sulfatase) Antibody (YA8288) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

IDS (Iduronate 2 sulfatase) Antibody (YA8288) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IDS (Iduronate 2 sulfatase).

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse
  • Calculated Molecular Weight Predicted band size: 59.2 kDa
Immunogen

Full length human recombinant protein of human IDS produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IDS is a Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate

  • Subcellular Localization

    Lysosome

  • Expression


    Tissue_Specificity: Liver, kidney, lung, and placenta

  • Isoforms & Post-Translational Modification

    P22304 has three isomers: P22304-1: 61873 Da (predicted); P22304-2: 38310 Da (predicted); P22304-3: 34893 Da (predicted).
    Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide丨The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity

  • Subunit

    Monomer (PubMed:28593992)

  • SwissProt ID

    P22304

  • Synonyms

    MPS2; SIDS

IDS (Iduronate 2 sulfatase) Antibody (YA8288) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • IDS (Iduronate 2 sulfatase) Antibody (YA8288) Product Image
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  • IDS (Iduronate 2 sulfatase) Antibody (YA8288) Product Image