IgM

By Targets:	Bacterial (1) Dihydroorotate Dehydrogenase (1) DNA/RNA Synthesis (1) Prostaglandin Receptor (1)
By Research Areas:	Infection (1) Inflammation/Immunology (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99214

Panobacumab KBPA101	Bacterial	Infection
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of *P. aeruginosa* .

HY-101813

Laflunimus HR325	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Prostaglandin Receptor	Inflammation/Immunology
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC₅₀ values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .

HY-113512

17-HDHA	Others	Inflammation/Immunology
17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 ⁺ CD38 ⁺ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells .

HY-120255

17(R)-HDHA 17(R)-HDoHE	Others	Inflammation/Immunology
17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .

Cat. No.	Product Name	Type

HY-P2149A

Concanavalin A (agarose)	Native Proteins
Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .

Concanavalin A (agarose)

Native Proteins

Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .

Cat. No.	Product Name

HY-K0213

Protein A Agarose 1 Publications Verification
MCE Protein A Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein A, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG, IgE, IgM.

Cat. No.	Product Name	Target	Research Area

HY-P99214

Panobacumab KBPA101	Bacterial	Infection
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of *P. aeruginosa* .

HY-P990162

*Anti-Mouse T15 VH and T15 VL regions of IgM* Antibody (HB33)**	Inhibitory Antibodies	Others
Anti-Mouse T15 VH and T15 VL regions of IgM Antibody (HB33) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse T15 VH and T15 VL regions of IgM.

HY-P990299

Anti-Mouse B220 Antibody (RA3.3A1/6.1)

Inhibitory Antibodies Others

Anti-Mouse B220 Antibody (RA3.3A1/6.1) is a rat-derived IgM type antibody inhibitor, targeting to mouse B220.

Anti-Mouse B220 Antibody (RA3.3A1/6.1)	Inhibitory Antibodies	Others
Anti-Mouse B220 Antibody (RA3.3A1/6.1) is a rat-derived IgM type antibody inhibitor, targeting to mouse B220.

HY-P99636

Gavilimomab ABX-CBL	Inhibitory Antibodies	Inflammation/Immunology
Gavilimomab (ABX-CBL) is an IgM murine monoclonal antibody that recognizes CD147 on the cell surface and initiates cell killing through complement-mediated lysis. Gavilimomab can be used for the research of graft-versus-host disease (GVHD) .

Recombinant Proteins Recommended:

IgM

Species:	Human (3) Mouse (1)
Tag:	His (2) Tag Free (1) Flag (2) Fc (1)
Source:	HEK293 (3) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P78271

	CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc) CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIgM; gp39; HIgM1; T-BAM; TRAP; IgM; IMD3; CD40 Ligand	Mouse	HEK293
	CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in mouse, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal hFc-tag.

HY-P78425

	CD40L/CD154/TRAP Protein, Human (HEK293, His-Flag) CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIgM; gp39; HIgM1; T-BAM; TRAP; IgM; IMD3; CD40 Ligand	Human	HEK293
	CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (HEK293, His-Flag) has a total length of 149 amino acids (M113-L261), is expressed in HEK392 cells with N-terminal His- and Flag-tag.

HY-P78102

	CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, His-Flag) CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIgM; gp39; HIgM1; T-BAM; TRAP; IgM; IMD3; CD40 Ligand	Human	HEK293
	CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, His-Flag) has a total length of 149 amino acids (M113-L261), is a biotinylated CD40L protein expressed in HEK392 cells with N-terminal His- and Flag-tag.

HY-P7144

	CD40L/CD154/TRAP Protein, Human rHuCD40L; CD154; TRAP; TNFSF5; CD40LG; CD40-L	Human	E. coli
	CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human has a total length of 149 amino acids (M113-L261), is expressed in E. coli cells with tag free.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Application	Reactivity

HY-P81317

Human IgM Antibody (YA1062)

Ig mu chain C region
ELISA, IHC-P Human
HY-P81473

IGJ Antibody (YA1218)

IGJ; Immunoglobulin J Chain; IGJ; Joining chain of multimeric IgA and IgM
IHC-P Human

HY-P80606

CD79a Antibody CD79A; IGA; MB1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD antigen CD79a	WB, IHC-F, IHC-P, ICC/IF	Human
CD79a Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to CD79a. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Biochemical Assay Reagents

MCE Kits

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Name
Email *

	Sorry, but the email address you supplied was invalid.