IGJ Antibody (YA1218)
(Synonyms: IGJ; Immunoglobulin J Chain; IGJ; Joining chain of multimeric IgA and IgM)IGJ Antibody (YA1218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGJ.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.40.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
IGJ Antibody (YA1218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGJ.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 18 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 18 kDa
A synthesized peptide derived from human IGJ
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.40.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
IGJ is a Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component
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Subcellular Localization
Secreted
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Subunit
Part of the secretory IgA (sIgA) complex that consists of two, four or five IgA monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteolytic product of PIGR) (PubMed:32029686). Part of the secretory IgM (sIgM) complex that consists of five IgM monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteolytic product of PIGR) (PubMed:32029686, PubMed:32029689). JCHAIN-containing IgM interacts (via CH4 domain) with FCRM (via Ig-like domain) (PubMed:37095205)
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SwissProt ID
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Synonyms
IGJ; Immunoglobulin J Chain; IGJ; Joining chain of multimeric IgA and IgM
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Research Field
Immunology
Documentation
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