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Results for "

Melittin

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

9

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0233
    Melittin
    10+ Cited Publications

    		 Phospholipase Inflammation/Immunology Cancer
    Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2 .
    <em>Melittin</em>
  • HY-P0233A
    Melittin TFA
    10+ Cited Publications

    		 Phospholipase Infection Cancer
    Melittin TFA is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2 .
    <em>Melittin</em> TFA
  • HY-P3914
    Cecropin A (1-7)-Melittin A (2-9)

    Oct-CA(1-7)M(2-9)

    		 Bacterial Infection
    Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
    Cecropin A (1-7)-<em>Melittin</em> A (2-9)
  • HY-P3906
    Melittin free acid

    		Fungal Apoptosis Phospholipase Reactive Oxygen Species Infection
    Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .
    <em>Melittin</em> free acid
  • HY-P3383
    Peceleganan

    PL-5

    		 Bacterial Infection
    Peceleganan (PL-5) is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan inhibits wound infection .
    Peceleganan
  • HY-P3383A
    Peceleganan acetate

    PL-5 acetate

    		 Bacterial Infection
    Peceleganan (PL-5) acetate is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan acetate inhibits wound infection .
    Peceleganan acetate
  • HY-101015A
    OBAA

    		Phospholipase Apoptosis Inflammation/Immunology
    OBAA is a potent phospholipase A2 (PLA2) inhibitor with an IC50 of 70 nM. OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei with an IC50 of 0.4 μM .
    OBAA
  • HY-P5552
    Melimine

    		Bacterial Parasite Fungal Infection
    Melimine is a hybrid antimicrobial peptide of Melittin (HY-P0233) and Protamine. Melimine is active against P. aeruginosa and S. aureus. Melimine has broad spectrum activity against bacteria, fungi and protozoa .
    Melimine
  • HY-P3328
    MDP1

    		Bacterial Infection
    MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
    MDP1
  • HY-P3328A
    MDP1 acetate

    		Bacterial Infection
    MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
    MDP1 acetate
  • HY-101015
    (2E)-OBAA

    (2E)-OBAA is a potent phospholipase A2 (PLA2) inhibitor, with an IC50 of 70 nM. (2E)-OBAA induces apoptosis of HUVEC cells. (2E)-OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei, with an IC50 of 0.4 μM .
    (2E)-OBAA
  • HY-132604
    Fazirsiran

    ARO-AAT

    		 Small Interfering RNA (siRNA) Metabolic Disease
    Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
    Fazirsiran
  • HY-132604A
    Fazirsiran sodium

    ARO-AAT sodium

    		 Small Interfering RNA (siRNA) Metabolic Disease
    Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
    Fazirsiran sodium

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