2. Anti-infection
  3. Bacterial
  4. Peceleganan acetate

Peceleganan acetate 

Cat. No.: HY-P3383A
Handling Instructions

Peceleganan acetate is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan acetate inhibits wound infection.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Peceleganan acetate Chemical Structure

Peceleganan acetate Chemical Structure

Size Price Stock Quantity
1 mg USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 290 In-stock
Estimated Time of Arrival: December 31
10 mg USD 470 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Purity & Documentation

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Description

Peceleganan acetate is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan acetate inhibits wound infection[1].

In Vitro

Peceleganan (24 h) acetate shows antibacterial activity with MICs of 2, 2, 4, 4, 4 and 8 μM against E. coli ATCC 25922, S. pneumonia ATCC 49619, K. pneumonia ATCC 700603, S. aureus ATCC 25923, S. epidermidis ATCC 12228 and P. aeruginosa ATCC 27853, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

Peceleganan (0.4 and 0.75 mg/mL for 100 μL; transdermal; twice daily for 3 days) acetate inhibits Staphylococcus aureus in the mouse infection model[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR male mice (20-25 g), S. aureus ATCC 25923 wound infection model[2]
Dosage: 0.4 and 0.75 mg/mL for 100 μL
Administration: Transdermal administration, twice daily for 3 days
Result: Significantly reduced the amount of bacteria.
Molecular Weight

2993.55

Appearance

Solid

Formula

C140H230N36O36
Sequence

Ac-Lys-Trp-Lys-Ser-Phe-Leu-Lys-Thr-Phe-Lys-Ser-Ala-Ala-Lys-Thr-Val-Leu-His-Thr-Ala-Leu-Lys-Ala-Ile-Ser-Ser-NH2
Sequence Shortening

Ac-KWKSFLKTFKSAAKTVLHTALKAISS-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (16.70 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3341 mL 1.6703 mL 3.3405 mL
5 mM 0.0668 mL 0.3341 mL 0.6681 mL
10 mM 0.0334 mL 0.1670 mL 0.3341 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PecelegananBacterialantimicrobialcecropin Amelittin Bwound infectionInhibitorinhibitorinhibit

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