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Pathways Recommended:	Protein Tyrosine Kinase/RTK

Results for "

Proline-rich tyrosine kinase 2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAK (2) Pyk2 (2) Reference Standards (1)
By Research Areas:	Cancer (2)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Targets Recommended: Pyk2 Btk Syk TNK1 Tyrosine Hydroxylase DYRK BRK FAK FLT3 Anaplastic lymphoma kinase (ALK)

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-10460

PF-431396 5+ Cited Publications	Pyk2 FAK	Cancer
PF-431396 is an orally active dual *focal adhesion kinase* (FAK)** and proline-rich tyrosine kinase 2 (PYK2) inhibitor, with IC₅₀ values of 2 nM and 11 nM, respectively .

HY-10460R

PF-431396 (Standard)	Reference Standards Pyk2 FAK	Cancer
PF-431396 (Standard) is the analytical standard of PF-431396 (HY-10460). This product is intended for research and analytical applications. PF-431396 is an orally active dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor, with IC₅₀ values of 2 nM and 11 nM, respectively .

Species:	Human (3)
Tag:	His (1) Tag Free (1) Avi (1) GST (1)
Source:	sf9 insect cells (2) Sf9 insect cells (1)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P706088

	PTK2B Protein, Human (Active, 331a.a, sf9) Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine kinase; RAFTK; FAK2; PYK2; RAFTK	Human	Sf9 insect cells

HY-P705867

	PTK2B Protein, Human (Active, Biotinylated, sf9, Avi) PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; Proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor Proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	sf9 insect cells

HY-P705866

	PTK2B Protein, Human (277a.a, sf9) PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; Proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor Proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	sf9 insect cells

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
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Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (2) Mouse (3) Rabbit (1) Dog (1) Pig (1)
Application:	IHC-P (4) ICC/IF (2) IF-Tissue (1) IP (1) IHC-F (1) WB (5) FC (1) ELISA (1)
Isotype:	IgG (2) IgG2a (2)
Conjugation:	Non-conjugated (5) Biotin (1)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Nombre del producto	Application	Reactivity	Image

HY-P80877

	PYK2 Antibody (YA682) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
	PYK2 Antibody (YA682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYK2.

HY-P85341

	PYK2 Antibody (YA5033) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P, ICC/IF, IF-Tissue, FC, IHC-F	Human, Mouse, Rat
	PYK2 Antibody (YA5033) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to PYK2.

HY-P85462

	PYK2 Antibody (YA5154) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB	Human, Mouse, Dog, Pig, Rabbit
	PYK2 Antibody (YA5154) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PYK2.

HY-P86140

	PYK2 Antibody (YA5832) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	PYK2 Antibody (YA5832) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PYK2.

HY-P80877A

	PYK2 Antibody (YA682)(PBS only) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor Proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
	PYK2 Antibody (YA682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYK2.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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