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RMI

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Adenylate Cyclase (1) Adrenergic Receptor (1) Antibiotic (1) DNA Alkylator/Crosslinker (1) Parasite (5) Phosphodiesterase (PDE) (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (8) Cardiovascular Disease (1) Infection (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

TOFA 5+ Cited Publications RMI14514; MDL14514	Acetyl-CoA Carboxylase	Cancer
TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ).

RMI-61140
RMI-61140 is an orally active neuroleptics. RMI-61140 decreases spontaneous motility and muscle tone in mice. RMI-61140 increases barbit urate-induced sleep and causes eyelid ptosis. RMI-61140 can be used for schizophrenia research .

RMI 10874	Antibiotic	Infection Cancer
RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.

RMI1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RMI1 Human Pre-designed siRNA Set A contains three designed siRNAs for RMI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RMI1 Human Pre-designed siRNA Set A RMI1 Human Pre-designed siRNA Set A

RMI2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RMI2 Human Pre-designed siRNA Set A contains three designed siRNAs for RMI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RMI2 Human Pre-designed siRNA Set A RMI2 Human Pre-designed siRNA Set A

Medroxalol RMI81968	Adrenergic Receptor	Cardiovascular Disease
Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist, blocks α- and β-adrenergic receptors. Medroxalol shows antihypertensive and vasodilating effects .

MDL12330A RMI12330A	Adenylate Cyclase Phosphodiesterase (PDE)	Others
MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase .

Eflornithine Maximum Cited Publications 10 Publications Verification DFMO; MDL71782; RMI71782; α-difluoromethylornithine	Parasite	Infection Cancer
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

Eflornithine hydrochloride DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride	Parasite	Infection Cancer
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

Eflornithine hydrochloride hydrate Maximum Cited Publications 10 Publications Verification DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate	Parasite	Cancer
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .

PIP-199	DNA Alkylator/Crosslinker	Cancer
PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC₅₀ of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics .

L-Eflornithine L-DFMO; L-RMI71782; L-α-difluoromethylornithine	Parasite	Cancer
L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

L-Eflornithine monohydrochloride L-DFMO monohydrochloride; ; L-RMI71782 monohydrochloride; L-α-difluoromethylornithine monohydrochloride	Parasite	Cancer
L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

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