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Results for "

Rta protein

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

2

Natural
Products

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-N0763
    Angelicin
    10+ Cited Publications

    Isopsoralen

    Apoptosis Virus Protease NF-κB p38 MAPK JNK Caspase Infection Inflammation/Immunology Cancer
    Angelicin is a furanocoumarin compound that functions as an inhibitor of NF-κB and MAPK signaling pathways, exhibiting anti-inflammatory, antiviral, and antitumor activities. It suppresses the lytic replication of γ-herpesviruses, such as MHV-68, early during viral infection, potentially inhibiting RTA gene expression (IC50=28.95 μM). Angelicin also mitigates inflammation by inhibiting the phosphorylation and nuclear translocation of NF-κB, and the phosphorylation of p38 and JNK. Furthermore, it induces apoptosis in neuroblastoma cells by downregulating anti-apoptotic proteins like Bcl-2, Bcl-xL, and Mcl-1, while activating caspase-9 and caspase-3.
    Angelicin
  • HY-P1890

    EBV Infection
    CEF14, EBV Rta Protein (28-37) is the HLA A24-restricted epitope from Epstein-Barr Virus Rta protein (28-37).
    CEF14, EBV Rta Protein (28-37)
  • HY-N9865

    Others Infection
    cis-Martynoside is a phenylpropanoid glycoside. Cis-Martynoside, in a mixture with trans-Martynoside, effectively inhibits the early activation of the lytic cycle of Epstein-Barr virus (EBV) and reduces the expression of Rta protein. cis-Martynoside can be used in research on EBV infection .
    cis-Martynoside

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