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Results for "

Sags

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Peptides

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12848S
    SAG-d3

    		Smo Cancer
    SAG-d3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM)[1].
    <em>SAG</em>-d3
  • HY-12848
    SAG
    Maximum Cited Publications
    18 Publications Verification

    		 Smo Cancer
    SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo .
    <em>SAG</em>
  • HY-157993
    SAG-524

    		HBV Infection
    SAG-524 is a potent oral small molecule HBV viral replication inhibitor. SAG-524 decreased HBV-DNA and HbsAg levels in supernatant of HepG2.2.15 cells, IC50 0.92 and 1.4 nM, respectively .
    <em>SAG</em>-524
  • HY-12848A
    (Rac)-SAG

    		Smo Cancer
    (Rac)-SAG is an isoform of SAG (HY-12848). SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo .
    (Rac)-<em>SAG</em>
  • HY-RS12415
    SAG Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SAG Human Pre-designed siRNA Set A contains three designed siRNAs for SAG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SAG Human Pre-designed siRNA Set A
    SAG Human Pre-designed siRNA Set A
  • HY-12848B
    SAG hydrochloride
    Maximum Cited Publications
    18 Publications Verification

    		 Smo Cancer
    SAG hydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG hydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo .
    <em>SAG</em> hydrochloride
  • HY-12848C
    SAG dihydrochloride
    Maximum Cited Publications
    18 Publications Verification

    		 Smo Cancer
    SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo .
    <em>SAG</em> dihydrochloride
  • HY-124899
    Hh-Ag1.5
    1 Publications Verification

    SAg1.5

    		 Hedgehog Metabolic Disease
    Hh-Ag1.5 (SAg1.5) is a potent Hedgehog (Hh) agonist with an EC50 of 1 nM . Hh-Ag1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure .
    Hh-Ag1.5
  • HY-117771
    DO34
    2 Publications Verification

    		 Others Metabolic Disease
    DO34 is a highly potent, selective and centrally active diacylglycerol lipase (DAGL) inhibitor, with an IC50 of 6 nM for DAGLα conversion of SAG to 2-AG, and an IC50 for DAGLβ.
    DO34
  • HY-110240
    IHR-1

    		Smo Others
    IHR-1 is a cell membrane impermeable Smo antagonist .
    IHR-1
  • HY-N7001
    Dehydrotomatine

    		Bacterial Fungal Infection
    Dehydrotomatine is a steroidal glycoalkaloid (SGA). α-tomatine and Dehydrotomatine accumulate in the mature green fruits, leaves, and flowers of tomatoes (Solanum lycopersicum) and function as defensive compounds against pathogens and predators. SGAs show toxic effects on fungi, bacteria, insects, and animals .
    Dehydrotomatine

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