SAG-524
Based on 1 Customer Validation
SAG-524 is a potent oral small molecule HBV viral replication inhibitor. SAG-524 decreased HBV-DNA and HbsAg levels in supernatant of HepG2.2.15 cells, IC50 0.92 and 1.4 nM, respectively.
For research use only. We do not sell to patients.
- Purity: 98.50%
- CAS No.: 2246696-89-7
- Formula: C30H32ClN5O4S
- Molecular Weight:594.12
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Infection Compound Library
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Antiviral Compound Library
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Orally Active Compound Library
HY-L061
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 2246696-89-7
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Appearance Solid
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Molecular Weight 594.12
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Formula C30H32ClN5O4S
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Color Light yellow to yellow
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SMILES
COCCN1CCN(CC1)C2=NC3=CC=C(C=C3S2)N4C=C(C(C=C4C5=CC(Cl)=C(C=C5)N6CCCC6)=O)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (168.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6832 mL | 8.4158 mL | 16.8316 mL | 42.0790 mL |
| 5 mM | 0.3366 mL | 1.6832 mL | 3.3663 mL | 8.4158 mL | |
| 10 mM | 0.1683 mL | 0.8416 mL | 1.6832 mL | 4.2079 mL | |
| 15 mM | 0.1122 mL | 0.5611 mL | 1.1221 mL | 2.8053 mL | |
| 20 mM | 0.0842 mL | 0.4208 mL | 0.8416 mL | 2.1040 mL | |
| 25 mM | 0.0673 mL | 0.3366 mL | 0.6733 mL | 1.6832 mL | |
| 30 mM | 0.0561 mL | 0.2805 mL | 0.5611 mL | 1.4026 mL | |
| 40 mM | 0.0421 mL | 0.2104 mL | 0.4208 mL | 1.0520 mL | |
| 50 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8416 mL | |
| 60 mM | 0.0281 mL | 0.1403 mL | 0.2805 mL | 0.7013 mL | |
| 80 mM | 0.0210 mL | 0.1052 mL | 0.2104 mL | 0.5260 mL | |
| 100 mM | 0.0168 mL | 0.0842 mL | 0.1683 mL | 0.4208 mL |
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