TdT

By Targets:	Antibiotic (5) Bacterial (5) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Fluorescent Dye (1) Fungal (5) Isotope-Labeled Compounds (2)
By Research Areas:	Cancer (1) Infection (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17395

Terbinafine hydrochloride Maximum Cited Publications 9 Publications Verification TdT 067 hydrochloride	Fungal Bacterial Antibiotic	Infection
Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a K_i of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17395A

Terbinafine Maximum Cited Publications 9 Publications Verification TdT 067	Fungal Bacterial Antibiotic	Infection
Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a K_i of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17395S

Terbinafine-d3 hydrochloride TdT 067-d₃ hydrochloride	Isotope-Labeled Compounds Fungal Bacterial Antibiotic	Infection
Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-17395B

Terbinafine lactate TdT 067 lactate	Antibiotic Fungal Bacterial	Infection
Terbinafine lactate (TDT 067 lactate) is an orally active and potent antifungal agent. Terbinafine lactate is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a K_i of 30 nM. Terbinafine lactate also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine (lactate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17395AS

Terbinafine-d7 TdT 067-d₇	Isotope-Labeled Compounds Fungal Bacterial Antibiotic	Infection
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-110139

Procaspase-IN-5	Others	Cancer
Procaspase-IN-5 is a human DNA polymerase λ inhibitor. Procaspase-IN-5 has DNA polymerization function and TdT function with an IC₅₀ value of 5.9 μM and 4.5 μM, respectively. Procaspase-IN-5 can be used for the research of cancer .

HY-D1721

Fluorescein-12-dATP	Fluorescent Dye	Others
Fluorescein-12-dATP is a fluorescent dye acting as the detection probe. Fluorescein-12-dATP can be used to label the thrombin-binding aptamers by catalytic polymerization of TdT (terminal deoxynucleotidyl transferase) . Fluorescein-12-dATP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1023

5-BrdUTP sodium salt 5-Bromo-2'-deoxyuridine 5'-triphosphate sodium salt	DNA/RNA Synthesis	Others
5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks.

HY-150145

Cy5-UTP	Biochemical Assay Reagents	Others
Cy5-UTP is a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be used to lable RNA probes through in vitro transcription (Excitation/Emission: 650/665 nm). Cy5-labeled mRNA emits orange fluorescence .

Cat. No.	Product Name	Type

HY-E70016

Terminal deoxyribonucleotidyltransferase TdT	Biochemical Assay Reagents
Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells .

HY-D1023

5-BrdUTP sodium salt 5-Bromo-2'-deoxyuridine 5'-triphosphate sodium salt	Biochemical Assay Reagents
5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks.

HY-150145

Cy5-UTP	Gene Sequencing and Synthesis
Cy5-UTP is a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be used to lable RNA probes through in vitro transcription (Excitation/Emission: 650/665 nm). Cy5-labeled mRNA emits orange fluorescence .

Cat. No.	Product Name

HY-KE8006

*Terminal Deoxynucleotidyl Transferase (TdT)*
Terminal Deoxynucleotidyl Transferase (TdT) is a template-independent DNA polymerase that catalyzes the binding of deoxynucleotides to the 3' hydroxyl end of oligonucleotides, single-stranded DNA, or double-stranded DNA.

Species:	Human (1)
Tag:	His (2)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71070

	TDT Protein, Human (His) DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltr; Terminal deoxynucleotidyltransferase; Terminal transferase; DNTT; TdT	Human	E. coli
	TDT protein, a template-independent DNA polymerase, non-specifically adds deoxynucleoside 5'-triphosphates to the 3'-end of a DNA initiator. It crucially contributes to in vivo processes, particularly adding nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during B- and T-cell maturation. TDT Protein, Human (His) is the recombinant human-derived TDT protein, expressed by E. coli , with N-6*His labeled tag. The total length of TDT Protein, Human (His) is 509 a.a., with molecular weight of ~62.0 kDa.

HY-P78946

	TDT Protein, Bos taurus (His)	Others	E. coli
	The TDT protein is a template-independent DNA polymerase that randomly adds deoxynucleoside 5'-triphosphates to the 3' end of the DNA initiator. Notably, its in vivo effects involve diversifying the immunoglobulin and T-cell receptor repertoire by adding nucleotides at the junction (N-region) of rearranged gene segments during B- and T-cell maturation. TDT Protein, Bos taurus (His) is the recombinant TDT protein, expressed by E. coli , with N-6*His labeled tag. TDT Protein, Bos taurus (His), has molecular weight of ~58.3 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-17395S

Terbinafine-d3 hydrochloride
Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

Terbinafine-d3 hydrochloride

Terbinafine-d₃ (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].

Cat. No.	Product Name	Application	Reactivity

HY-P81810

DNA Nucleotidylexotransferase Antibody (YA1555)

DNA nucleotidylexotransferase; DNTT; TdT; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase
WB Human

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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