21 Results for "

Tos-PEG3

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Tos-PEG3" in MCE Product Catalog:

Cat. No.: HY-23408
CAS No.: 77544-68-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports .
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Cat. No.: HY-140004
CAS No.: 178685-33-1
Purity:  99.15%
Research Areas:  

Cancer

Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG3-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-P5112A
Synonyms: Azido-PEG3-FLAG TFA
Research Areas:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No.: HY-45018
CAS No.: 1530778-24-5
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-P5112
CAS No.: 2243206-95-1
Synonyms: Azido-PEG3-FLAG
Research Areas:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No.: HY-169089
Target:  

Drug Derivative

Research Areas:  

Cancer

RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
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Cat. No.: HY-128805
CAS No.: 206265-94-3
Purity:  99.66%
Synonyms: PROTAC Linker 9
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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Cat. No.: HY-128802
CAS No.: 855120-17-1
Synonyms: PROTAC Linker 6
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-O-C1-CH3COO (PROTAC Linker 6) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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Cat. No.: HY-P11270
CAS No.: 2843676-09-3
Synonyms: BGM0504; BG128
Research Areas:  

Metabolic Disease

Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
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Cat. No.: HY-W043277
CAS No.: 62921-74-8
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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Cat. No.: HY-W013731
CAS No.: 19249-03-7
Synonyms: Bis-Tos-PEG3
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Triethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-W044211
CAS No.: 84131-04-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-Bn is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-130674
CAS No.: 1581248-63-6
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-140375
CAS No.: 1239588-09-0
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-169089A
Target:  

Drug Derivative

Research Areas:  

Cancer

RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
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Cat. No.: HY-P10319
Target:  

PKA

Research Areas:  

Cardiovascular Disease Cancer

RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
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Cat. No.: HY-W800661
CAS No.: 2468714-93-2
Research Areas:  

Others

Tos-PEG3-methyl ester is a PEG linker with tosyl and methyl ester moieties. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound. Methyl ester can be hydrolyzed under strong basic condition.
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Cat. No.: HY-181737
Research Areas:  

Others

E3 Ligase Ligand-linker Conjugate 225 is an E3 ligase ligand-linker conjugate used for the synthesis of PROTACs; it consists of the PEG-based linker Bis-Tos-PEG3 (HY-W013731) and the VHL-type E3 ubiquitin ligase ligand VH 101 thiol (HY-47851). E3 Ligase Ligand-linker Conjugate 225 can be further coupled with a target protein ligand—such as MT-4 (HY-128595)—to synthesize the PROTAC TG2 Degrader-3 (HY-181732) .
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Cat. No.: HY-P11488
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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