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Pathways Recommended: Vitamin D Related/Nuclear Receptor PI3K/Akt/mTOR
Results for "

Vitamin K Epoxide Reductase

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Recombinant Proteins

1

Isotope-Labeled Compounds

Targets Recommended:
Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-111186
    Flocoumafen

    WL 108366

    		 Glucocorticoid Receptor MMP VKOR Others
    Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .
    Flocoumafen
  • HY-113164
    Vitamin K1 2,3-epoxide

    		Endogenous Metabolite Others
    Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting .
    Vitamin K1 2,3-epoxide
  • HY-14854
    Tecarfarin

    ATI-5923

    		 VKOR Cardiovascular Disease
    Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .
    Tecarfarin
  • HY-113164S
    Vitamin K1 2,3-epoxide-d7

    		Isotope-Labeled Compounds Others
    Vitamin K1 2,3-epoxide-d7 is the deuterium labeled Vitamin K1 2,3-epoxide .
    Vitamin K1 2,3-epoxide-d7
  • HY-134999
    10-Hydroxywarfarin

    		Drug Metabolite Cytochrome P450 VKOR Metabolic Disease
    10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively .
    10-Hydroxywarfarin
  • HY-111186R
    Flocoumafen (Standard)

    WL 108366 (Standard)

    		 Reference Standards VKOR Glucocorticoid Receptor MMP Others
    Flocoumafen (Standard) is the analytical standard of Flocoumafen. This product is intended for research and analytical applications. Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .
    Flocoumafen (Standard)
  • HY-121814A
    (R)-Acenocoumarol

    (R)-Acenocoumarin; (R)-Nicoumalone

    		 VD/VDR Cardiovascular Disease
    (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting and orally active anticoagulant, like Warfarin (HY-B0687), works by inhibiting vitamin K epoxide reductase. (R)-Acenocoumarol has a greater in vivo anticoagulant potency than Warfarin. (R)-Acenocoumarol has a single chiral center that produces two different enantiomeric forms. (R)-Acenocoumarol has a longer plasma elimination half-life (6.6 h) and a slower plasma clearance rate (1.9 L/h) than the (S)-enantiomer, resulting in a stronger in vivo anticoagulant effect.
    (R)-Acenocoumarol

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