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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
X-ray crystal structure
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "X-ray crystal structure" in MCE Product Catalog:
Category:
Alkaloids Aloe africana Liliaceae Other Diseases Pyridine Alkaloids Plants Disease Research Fields
Target:
Cat. No.: HY-124339
CAS No.: 2092913-64-7
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Research Areas:
JNJ525 is a TNFα inhibitor with IC50 values of 1.2 μM and 1.1 μM against TNFR1 and TNFR2, respectively. JNJ525 forms ordered aggregates and induces quaternary structural transition of TNFα, thereby blocking the protein-protein interaction between TNFα and its receptors. The inhibitory activity of JNJ525 is completely lost in the presence of 0.1% Triton X-100 .
Cat. No.: HY-W717743
CAS No.: 913528-04-8
Cat. No.: HY-121125
CAS No.: 64274-28-8
Category:
Plantaginaceae Iridoids Terpenoids Plants Pseudolysimachion linariifolium subsp. dilatatum (Nakai & Kitag.) D. Y. Hong
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Cat. No.: HY-120631A
CAS No.: 841302-51-0
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Research Areas:
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
Cat. No.: HY-N11940
CAS No.: 77174-33-5
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Cat. No.: HY-153047
CAS No.: 1984788-85-3
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Research Areas:
Trypsin-IN-2 (Compound 12) is an efficient and highly selective inhibitor of human trypsin, with an IC₅₀ of 8 nM. Trypsin-IN-2 can be used for research on pancreatic cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
